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GSG2 抗体 (AA 323-352)

GSG2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB3404 unconjugated
产品编号 ABIN1882168
发货至: 中国
  • 抗原 See all GSG2 抗体
    GSG2 (Germ Cell Associated 2 (Haspin) (GSG2))
    抗原表位
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 323-352
    适用
    • 23
    • 3
    • 3
    • 2
    • 1
    宿主
    • 25
    • 2
    克隆类型
    • 26
    • 1
    多克隆
    标记
    • 13
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GSG2 antibody is un-conjugated
    应用范围
    • 13
    • 8
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This Haspin GSG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323~352 amino acids from the central region of human haspin.
    克隆位点
    RB3404
    亚型
    Ig Fraction
    Top Product
    Discover our top product GSG2 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Dai, Sultan, Taylor, Higgins: "The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment." in: Genes & development, Vol. 19, Issue 4, pp. 472-88, (2005) (PubMed).

    Higgins: "The Haspin gene: location in an intron of the integrin alphaE gene, associated transcription of an integrin alphaE-derived RNA and expression in diploid as well as haploid cells." in: Gene, Vol. 267, Issue 1, pp. 55-69, (2001) (PubMed).

    Tanaka, Iguchi, Nakamura, Kohroki, de Carvalho, Nishimune: "Cloning and characterization of human haspin gene encoding haploid germ cell-specific nuclear protein kinase." in: Molecular human reproduction, Vol. 7, Issue 3, pp. 211-8, (2001) (PubMed).

  • 抗原
    GSG2 (Germ Cell Associated 2 (Haspin) (GSG2))
    别名
    Haspin GSG2 (GSG2 产品)
    别名
    BcDNA:LD07633 antibody, CG40080 antibody, Dmel\\CG40080 antibody, haspin antibody, NV16901 antibody, HASPIN antibody, Haspin antibody, putative serine/threonine-protein kinase haspin homolog antibody, histone H3 associated protein kinase antibody, CG40080 gene product from transcript CG40080-RA antibody, uncharacterized LOC100122327 antibody, LOC552287 antibody, HASPIN antibody, Haspin antibody, LOC100122327 antibody
    背景
    Post-translational modifications of conserved N-terminal tail residues in histones regulate many aspects of chromosome activity. Mitotic phosphorylation of H3 Thr 3 occurs in prophase and dephosphorylation during anaphase. Haspin, a dual serine/threonine kinase, plays an important role in regulation of chromosome and spindle function during mitosis and meiosis via its function in phosphorylation of the threonine residue in the third position of histone 3 (Thr3).
    分子量
    88495
    NCBI登录号
    NP_114171
    UniProt
    Q8TF76
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