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ATG4C 抗体 (C-Term)

Name: ATG4C 抗体 (C-Term)
SKU: ABIN1882160
Availability: OutOfStock

ATG4C 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB7499 unconjugated

Western blot analysis of lysates from Hela cell line and mouse liver tissue lysate(from left to right), using G4C Antibody 1810C. (ATG4C 抗体 (C-Term))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. (ATG4C 抗体 (C-Term))

IHC (p)

2 images

(3 references)

产品编号 ABIN1882160

发货至: 中国

Datasheet as PDF

抗原 See all ATG4C 抗体

ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))
抗原表位
15

13

6

3

3

2

2

2

1

1

1

1

1

1
AA 419-448, C-Term
适用
59

35

2

2

2

1

1
人, 小鼠
宿主
53

10

2

1
兔
Compatible Secondaries
克隆类型
58

8
多克隆
标记
26

5

5

4

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This ATG4C antibody is un-conjugated
应用范围
54

22

18

13

13

12

12

8

3

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This ATG4C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 419-448 amino acids from the C-terminal region of human ATG4C.

克隆位点

RB7499

亚型

Ig Fraction

Top Product

Discover our top product ATG4C Primary Antibody
anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (AA 321-458) antibody
ATG4C 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E10H7 unconjugated

anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (AA 419-448) antibody
ATG4C 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (N-Term) antibody
ATG4C 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (N-Term) antibody (HRP)
ATG4C 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal HRP

anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (N-Term) antibody (FITC)
ATG4C 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal FITC

anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (N-Term) antibody (Biotin)
ATG4C 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Biotin

anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (N-Term) antibody (PE)
ATG4C 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal PE

anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (N-Term) antibody (PerCP)
ATG4C 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal PerCP

anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (N-Term) antibody (Atto 488)
ATG4C 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Atto 488

anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (N-Term) antibody (Atto 594)
ATG4C 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Atto 594

应用备注

WB: 1:1000. IHC-P: 1:50~100

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Ma, Panda, Lin: "Temporal orchestration of circadian autophagy rhythm by C/EBP?." in: The EMBO journal, Vol. 30, Issue 22, pp. 4642-51, (2012) (PubMed).

Norman, Cohen, Bampton: "The in vitro cleavage of the hAtg proteins by cell death proteases." in: Autophagy, Vol. 6, Issue 8, pp. 1042-56, (2010) (PubMed).

Shintani, Klionsky: "Autophagy in health and disease: a double-edged sword." in: Science (New York, N.Y.), Vol. 306, Issue 5698, pp. 990-5, (2004) (PubMed).
抗原

ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))

别名

ATG4C (ATG4C 产品)

别名

apg4c antibody, atg4cl antibody, zgc:86888 antibody, wu:fc56g07 antibody, APG4-C antibody, APG4C antibody, AUTL1 antibody, AUTL3 antibody, Apg4-C antibody, Apg4c antibody, Atg4cl antibody, Autl1 antibody, autophagy related 4C cysteine peptidase antibody, autophagy related 4C, cysteine peptidase antibody, cysteine protease ATG4C antibody, ATG4C antibody, atg4c antibody, Tsp_15996 antibody, Atg4c antibody

背景

Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG4 is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.

分子量

52497

NCBI登录号

NP_116241, NP_835739

UniProt

Q96DT6

途径

Autophagy