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- 抗原 See all UVRAG 抗体
- UVRAG (UV Radiation Resistance Associated Gene (UVRAG))
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抗原表位
- AA 540-569, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UVRAG antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This UVRAG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 540-569 amino acids from the C-terminal region of human UVRAG.
- 克隆位点
- RB13045
- 亚型
- Ig Fraction
- Top Product
- Discover our top product UVRAG Primary Antibody
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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Autophagic induction of amyotrophic lateral sclerosis-linked Cu/Zn superoxide dismutase 1 G93A mutant in NSC34 cells." in: Neural regeneration research, Vol. 9, Issue 1, pp. 16-24, (2014) (PubMed).
: "RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly." in: Cell, Vol. 144, Issue 2, pp. 253-67, (2011) (PubMed).
: "Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG." in: Nature cell biology, Vol. 8, Issue 7, pp. 688-99, (2006) (PubMed).
: "Report of the Third International Workshop on Y Chromosome Mapping 1997. Heidelberg, Germany, April 13-16, 1997." in: Cytogenetics and cell genetics, Vol. 79, Issue 1-2, pp. 1-20, (1998) (PubMed).
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Autophagic induction of amyotrophic lateral sclerosis-linked Cu/Zn superoxide dismutase 1 G93A mutant in NSC34 cells." in: Neural regeneration research, Vol. 9, Issue 1, pp. 16-24, (2014) (PubMed).
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- 抗原
- UVRAG (UV Radiation Resistance Associated Gene (UVRAG))
- 别名
- UVRAG (UVRAG 产品)
- 背景
- UVRAG complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving the UVAG gene are associated with left-right axis malformation and mutations in the gene have been associated with colon cancer.
- 分子量
- 78151
- NCBI登录号
- NP_003360
- UniProt
- Q9P2Y5
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