PIAS3 抗体 (AA 588-619)
(7 references)-
- 抗原 See all PIAS3 抗体
- PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))
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抗原表位
- AA 588-619
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PIAS3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- M, Rat
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This PIAS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 588-619 amino acids of human PIAS3.
- 克隆位点
- RB0673
- 亚型
- Ig Fraction
- Top Product
- Discover our top product PIAS3 Primary Antibody
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anti-Protein Inhibitor of Activated STAT, 3 (PIAS3) (N-Term) antibody
PIAS3 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 3 (PIAS3) (AA 453-550) antibodyPIAS3 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 4F12 unconjugated
anti-Protein Inhibitor of Activated STAT, 3 (PIAS3) (AA 452-628) antibodyPIAS3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 3 (PIAS3) (N-Term) antibodyPIAS3 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 3 (PIAS3) (AA 399-628) antibodyPIAS3 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 3 (PIAS3) (N-Term) antibodyPIAS3 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 3 (PIAS3) (AA 548-597) antibodyPIAS3 适用: 人, 大鼠, 犬, Cow, Pig, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 3 (PIAS3) (AA 95-126), (N-Term) antibodyPIAS3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB0671 unconjugated
anti-Protein Inhibitor of Activated STAT, 3 (PIAS3) (C-Term) antibodyPIAS3 适用: 人, 大鼠, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 3 (PIAS3) (AA 453-550) antibodyPIAS3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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: "SUMOylation of the GTPase Rac1 is required for optimal cell migration." in: Nature cell biology, Vol. 12, Issue 11, pp. 1078-85, (2010) (PubMed).
: "Arsenic trioxide affects signal transducer and activator of transcription proteins through alteration of protein tyrosine kinase phosphorylation." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 12, Issue 22, pp. 6817-25, (2006) (PubMed).
: "ATBF1 enhances the suppression of STAT3 signaling by interaction with PIAS3." in: Biochemical and biophysical research communications, Vol. 314, Issue 1, pp. 97-103, (2004) (PubMed).
: "Activation of Smad transcriptional activity by protein inhibitor of activated STAT3 (PIAS3)." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 1, pp. 99-104, (2004) (PubMed).
: "Down-regulation of SHP1 and up-regulation of negative regulators of JAK/STAT signaling in HTLV-1 transformed cell lines and freshly transformed human peripheral blood CD4+ T-cells." in: Leukemia research, Vol. 28, Issue 1, pp. 71-82, (2003) (PubMed).
: "Molecular interactions between STAT3 and protein inhibitor of activated STAT3, and androgen receptor." in: Biochemical and biophysical research communications, Vol. 306, Issue 2, pp. 610-5, (2003) (PubMed).
: "Isolation and chromosomal assignment of a human gene encoding protein inhibitor of activated STAT3 (PIAS3)." in: Journal of human genetics, Vol. 44, Issue 3, pp. 193-6, (1999) (PubMed).
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: "SUMOylation of the GTPase Rac1 is required for optimal cell migration." in: Nature cell biology, Vol. 12, Issue 11, pp. 1078-85, (2010) (PubMed).
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- 抗原
- PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))
- 别名
- PIAS3 (PIAS3 产品)
- 别名
- PIAS3 antibody, Pias3l antibody, ZMIZ5 antibody, protein inhibitor of activated STAT 3 antibody, protein inhibitor of activated STAT, 3 antibody, protein inhibitor of activated STAT 3 L homeolog antibody, PIAS3 antibody, pias3 antibody, Pias3 antibody, pias3.L antibody
- 背景
- PIAS3 is a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor, catalyzing the covalent attachment of a SUMO protein to specific target substrates. PIAS3 plays a crucial role as a transcriptional coregulator in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. The effects of this transcriptional coregulation, transactivation or silencing, may vary depending upon the biological context.
- 分子量
- 68017
- NCBI登录号
- NP_006090
- UniProt
- Q9Y6X2
- 途径
- JAK/STAT Signaling
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