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PIK3CA 抗体 (C-Term)

PIK3CA 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB01702 unconjugated
产品编号 ABIN1882113
发货至: 中国
  • 抗原 See all PIK3CA 抗体
    PIK3CA (Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA))
    抗原表位
    • 15
    • 15
    • 13
    • 10
    • 9
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1019-1050, C-Term
    适用
    • 83
    • 61
    • 32
    • 26
    • 15
    • 1
    宿主
    • 85
    • 6
    • 2
    克隆类型
    • 80
    • 13
    多克隆
    标记
    • 28
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    • 4
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    • 2
    • 2
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
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    This PIK3CA antibody is un-conjugated
    应用范围
    • 68
    • 34
    • 26
    • 26
    • 23
    • 11
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    预测反应
    B
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This PI3KCA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1019-1050 amino acids from the C-terminal region of human PI3KCA.
    克隆位点
    RB01702
    亚型
    Ig Fraction
    Top Product
    Discover our top product PIK3CA Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze-thaw cycles.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
    有效期
    6 months
  • Zhai, Zhao, Ye, Huang, Tian, Wu, Lin, Lin: "Expression of PIK3CA and FOXP1 in gastric and intestinal non-Hodgkin's lymphoma of mucosa-associated lymphoid tissue type." in: Tumour biology, Vol. 32, Issue 5, pp. 913-20, (2011) (PubMed).

    Tiwari, Choi, Matsuzawa, Pypaert, MacMicking: "Targeting of the GTPase Irgm1 to the phagosomal membrane via PtdIns(3,4)P(2) and PtdIns(3,4,5)P(3) promotes immunity to mycobacteria." in: Nature immunology, Vol. 10, Issue 8, pp. 907-17, (2009) (PubMed).

    Singh, Reddy, Goberdhan, Walsh, Dao, Ngai, Chou, O-Charoenrat, Levine, Rao, Stoffel: "p53 regulates cell survival by inhibiting PIK3CA in squamous cell carcinomas." in: Genes & development, Vol. 16, Issue 8, pp. 984-93, (2002) (PubMed).

  • 抗原
    PIK3CA (Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA))
    别名
    PI3KCA (PIK3CA 产品)
    别名
    CLOVE antibody, CWS5 antibody, MCAP antibody, MCM antibody, MCMTC antibody, PI3K antibody, p110-alpha antibody, C-P3K antibody, PI3-kinase antibody, PI3K-alpha antibody, pi3-k antibody, pi3k antibody, AA414921 antibody, C530050K14 antibody, p50alpha antibody, p55alpha antibody, p85alpha antibody, 6330412C24Rik antibody, caPI3K antibody, p110 antibody, p110alpha antibody, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha antibody, Phosphoinositide-3-kinase, catalytic, alpha polypeptide antibody, phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha antibody, phosphoinositide-3-kinase regulatory subunit 1 antibody, PIK3CA antibody, GL50803_14855 antibody, pik3ca antibody, Pik3ca antibody, Pik3r1 antibody
    背景
    Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. This protein represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. PI3KCA has been found to be oncogenic and has been implicated in cervical cancers.
    分子量
    124284
    NCBI登录号
    NP_006209
    UniProt
    P42336
    途径
    PI3K-Akt Signaling, RTK signaling, TCR Signaling, AMPK Signaling, Interferon-gamma Pathway, TLR signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, VEGF Signaling
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