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DNAJB1 抗体

DNAJB1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB1770 unconjugated
产品编号 ABIN1882092
发货至: 中国
  • 抗原 See all DNAJB1 抗体
    DNAJB1 (DnaJ (Hsp40) Homolog, Subfamily B, Member 1 (DNAJB1))
    适用
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    人, 小鼠
    宿主
    • 56
    • 38
    克隆类型
    • 56
    • 38
    多克隆
    标记
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    This DNAJB1 antibody is un-conjugated
    应用范围
    • 79
    • 42
    • 40
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    • 8
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    • 2
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This HSP40 antibody is generated from rabbits immunized with a recombinant protein encoding full length of human HSP40.
    克隆位点
    RB1770
    亚型
    Ig Fraction
    Top Product
    Discover our top product DNAJB1 Primary Antibody
  • 应用备注
    WB: 1:4000. IHC-P: 1:50~100. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Ohtsuka, Hata: "Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature." in: Cell stress & chaperones, Vol. 5, Issue 2, pp. 98-112, (2001) (PubMed).

    Hata, Ohtsuka: "Characterization of HSE sequences in human Hsp40 gene: structural and promoter analysis." in: Biochimica et biophysica acta, Vol. 1397, Issue 1, pp. 43-55, (1998) (PubMed).

    Hata, Okumura, Seto, Ohtsuka: "Genomic cloning of a human heat shock protein 40 (Hsp40) gene (HSPF1) and its chromosomal localization to 19p13.2." in: Genomics, Vol. 38, Issue 3, pp. 446-9, (1997) (PubMed).

  • 抗原
    DNAJB1 (DnaJ (Hsp40) Homolog, Subfamily B, Member 1 (DNAJB1))
    别名
    HSP40 (DNAJB1 产品)
    背景
    DnaJ (Hsp40) belongs to the DnaJ-class of molecular chaperones with a C-terminal Zn finger domain. HSP40 (DnaJ) together with DnaK and GrpE form a molecular chaperone that is involved in formation of protein complexes, protein folding, prevention of protein aggregation, and protein turnover and export. Several human neurodegenerative diseases involve the expansion of a polyglutamine within the disease proteins. Molecular chaperones such as HSP40 complexes can modulate polyglutamine pathogenesis In transgenic Drosophila disease models of Machado-Joseph disease and Huntington disease Hdj1, the Drosophila homolog to human HSP40, demonstrates substrate specificity for polyglutamine proteins suppression in combination with other molecular chapterones of neurotoxicity, and altered solubility of mutant polyglutamine proteins.
    分子量
    38044
    NCBI登录号
    NP_006136
    UniProt
    P25685
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