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- 抗原 See all DNAJB1 抗体
- DNAJB1 (DnaJ (Hsp40) Homolog, Subfamily B, Member 1 (DNAJB1))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DNAJB1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This HSP40 antibody is generated from rabbits immunized with a recombinant protein encoding full length of human HSP40.
- 克隆位点
- RB1770
- 亚型
- Ig Fraction
- Top Product
- Discover our top product DNAJB1 Primary Antibody
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- 应用备注
- WB: 1:4000. IHC-P: 1:50~100. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature." in: Cell stress & chaperones, Vol. 5, Issue 2, pp. 98-112, (2001) (PubMed).
: "Characterization of HSE sequences in human Hsp40 gene: structural and promoter analysis." in: Biochimica et biophysica acta, Vol. 1397, Issue 1, pp. 43-55, (1998) (PubMed).
: "Genomic cloning of a human heat shock protein 40 (Hsp40) gene (HSPF1) and its chromosomal localization to 19p13.2." in: Genomics, Vol. 38, Issue 3, pp. 446-9, (1997) (PubMed).
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Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature." in: Cell stress & chaperones, Vol. 5, Issue 2, pp. 98-112, (2001) (PubMed).
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- 抗原
- DNAJB1 (DnaJ (Hsp40) Homolog, Subfamily B, Member 1 (DNAJB1))
- 别名
- HSP40 (DNAJB1 产品)
- 别名
- HSPF1 antibody, Hdj1 antibody, Hsp40 antibody, RSPH16B antibody, Sis1 antibody, CG10578 antibody, DNAJ-1 antibody, DNAJ1 antibody, DROJ1 antibody, Dmel\\CG10578 antibody, DnaJ1 64EF antibody, DroJ1 antibody, EU3500 antibody, HSP40 antibody, HSP40/HDJ1 antibody, Hsp-40 antibody, anon-WO0140519.166 antibody, anon-WO0172774.135 antibody, dHDJ1 antibody, dHDJ1/HSP40 antibody, dHdj1 antibody, dhdJ1 antibody, dhdj-1 antibody, dhdj1 antibody, dnaJ-1 antibody, droj1 antibody, hsp40 antibody, dnajb4 antibody, hdj1 antibody, hspf1 antibody, sis1 antibody, DnaJ-5 antibody, MAS5 antibody, dnaJ antibody, 0610007I11Rik antibody, dnajb1 antibody, zf-Hsp40 antibody, zgc:101068 antibody, DnaJ heat shock protein family (Hsp40) member B1 antibody, DnaJ-like-1 antibody, DnaJ (Hsp40) homolog 5 antibody, type I HSP40 co-chaperone YDJ1 antibody, DnaJ protein antibody, molecular chaperone DnaJ antibody, DnaJ (Hsp40) homolog, subfamily B, member 1a antibody, DNAJB1 antibody, Dnajb1 antibody, DnaJ-1 antibody, dnajb1 antibody, DnaJ-5 antibody, YDJ1 antibody, dnaJ antibody, dnajb1a antibody
- 背景
- DnaJ (Hsp40) belongs to the DnaJ-class of molecular chaperones with a C-terminal Zn finger domain. HSP40 (DnaJ) together with DnaK and GrpE form a molecular chaperone that is involved in formation of protein complexes, protein folding, prevention of protein aggregation, and protein turnover and export. Several human neurodegenerative diseases involve the expansion of a polyglutamine within the disease proteins. Molecular chaperones such as HSP40 complexes can modulate polyglutamine pathogenesis In transgenic Drosophila disease models of Machado-Joseph disease and Huntington disease Hdj1, the Drosophila homolog to human HSP40, demonstrates substrate specificity for polyglutamine proteins suppression in combination with other molecular chapterones of neurotoxicity, and altered solubility of mutant polyglutamine proteins.
- 分子量
- 38044
- NCBI登录号
- NP_006136
- UniProt
- P25685
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