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FKBP1A 抗体 (C-Term)

Name: FKBP1A 抗体 (C-Term)
SKU: ABIN1882082
Availability: OutOfStock

FKBP1A 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19307 unconjugated

Western blot analysis of FKBP1A antibody (C-term) (ABIN1882082 and ABIN2841885) in Jurkat cell line lysates (35 μg/lane). (FKBP1A 抗体 (C-Term))

FKBP1A Antibody (C-term) (ABIN1882082 and ABIN2841885) flow cytometric analysis of MDA-M cells (right histogram) compared to a negative control cell (left histogram). (FKBP1A 抗体 (C-Term))

FACS

Western blot analysis of FKBP1A (arrow) using rabbit polyclonal FKBP1A Antibody (C-term) (ABIN1882082 and ABIN2841885). (FKBP1A 抗体 (C-Term))

FKBP1A Antibody (C-term) (ABIN1882082 and ABIN2841885) IHC analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. (FKBP1A 抗体 (C-Term))

IHC (p)

4 images

(2 references)

产品编号 ABIN1882082

发货至: 中国

Datasheet as PDF

抗原 See all FKBP1A 抗体

FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))
抗原表位
9

7

5

4

3

2

1

1

1

1
AA 55-83, C-Term
适用
56

28

21

5

4

3

3

2

2

2

2

1

1
人
宿主
55

8
兔
Compatible Secondaries
克隆类型
48

15
多克隆
标记
27

9

8

4

2

2

2

2

2

2

1

1

1
This FKBP1A antibody is un-conjugated
应用范围
33

22

18

8

7

6

4

3

3

2

1

1
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

预测反应

B, Rb

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This FKBP1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-83 amino acids from the C-terminal region of human FKBP1A.

克隆位点

RB19307

亚型

Ig Fraction
anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) (AA 1-108) antibody
FKBP1A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E5-A12 unconjugated

anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) (AA 1-108) antibody
FKBP1A 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) (AA 2-103) antibody
FKBP1A 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) antibody
FKBP1A 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated

anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) (AA 2-108) antibody
FKBP1A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) (AA 2-108) antibody
FKBP1A 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C2 unconjugated

anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) (N-Term) antibody
FKBP1A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) antibody
FKBP1A 适用: 人 WB 宿主: 兔 Monoclonal unconjugated

anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) (AA 43-74) antibody
FKBP1A 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) antibody
FKBP1A 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Gerard, Debyser, Desender, Baert, Brandt, Baekelandt, Engelborghs: "FK506 binding protein 12 differentially accelerates fibril formation of wild type alpha-synuclein and its clinical mutants A30P or A53T." in: Journal of neurochemistry, Vol. 106, Issue 1, pp. 121-33, (2008) (PubMed).

Shor, Zhang, Toral-Barza, Lucas, Abraham, Gibbons, Yu: "A new pharmacologic action of CCI-779 involves FKBP12-independent inhibition of mTOR kinase activity and profound repression of global protein synthesis." in: Cancer research, Vol. 68, Issue 8, pp. 2934-43, (2008) (PubMed).
抗原

FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

别名

FKBP1A (FKBP1A 产品)

别名

12kDa antibody, FKBP12 antibody, FKBP12-T1 antibody, FKBP12-T2 antibody, Fkbp antibody, Fkbp1 antibody, mFKBP1 antibody, mFKBP12 antibody, FKBP-12 antibody, FKBP-1A antibody, FKBP1 antibody, Rotamase antibody, Fkbp12 antibody, ARABIDOPSIS THALIANA FK506-BINDING PROTEIN 12 antibody, ATFKBP12 antibody, FK506-binding protein 12 antibody, IMMUNOPHILIN antibody, MSJ1.19 antibody, MSJ1_19 antibody, PKC12 antibody, PKCI2 antibody, PPIASE antibody, FKBP1B antibody, Fkbp2 antibody, fj02g10 antibody, zgc:73373 antibody, wu:fj02g10 antibody, FKBP1A antibody, Bmfkbp13 antibody, zgc:103752 antibody, FK506 binding protein 1a antibody, FK506 binding protein 1A antibody, FK506-binding protein antibody, FK506-binding protein 12 antibody, FK506 binding protein 1Aa antibody, FK506 binding protein 1C antibody, FK506-binding protein 59 antibody, FK506 binding protein like antibody, FK506 binding protein 1A L homeolog antibody, FK506 binding protein 1Ab antibody, Fkbp1a antibody, FKBP1A antibody, Fkbp12 antibody, FKBP12 antibody, fkbp1aa antibody, FKBP1C antibody, EHI_180160 antibody, LOC5573443 antibody, Fkbp13 antibody, FKBPL antibody, fkbp1a.L antibody, fkbp1ab antibody

背景

FKBP12 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.

分子量

11951

NCBI登录号

NP_000792, NP_463460

UniProt

P62942

途径

Negative Regulation of Transporter Activity, Methionine Biosynthetic Process