DRAK2 抗体 (C-Term)
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- 抗原 See all DRAK2 (STK17B) 抗体
- DRAK2 (STK17B) (serine/threonine Kinase 17b (STK17B))
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抗原表位
- AA 342-371, C-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DRAK2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This DRAK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 342-371 amino acids from the C-terminal region of human DRAK2.
- 克隆位点
- RB3049
- 亚型
- Ig Fraction
- Top Product
- Discover our top product STK17B Primary Antibody
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- 应用备注
- IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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Drak2 is upstream of p70S6 kinase: its implication in cytokine-induced islet apoptosis, diabetes, and islet transplantation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 8, pp. 4762-70, (2009) (PubMed).
: "Transgenic drak2 overexpression in mice leads to increased T cell apoptosis and compromised memory T cell development." in: The Journal of biological chemistry, Vol. 281, Issue 18, pp. 12587-95, (2006) (PubMed).
: "DRAKs, novel serine/threonine kinases related to death-associated protein kinase that trigger apoptosis." in: The Journal of biological chemistry, Vol. 273, Issue 44, pp. 29066-71, (1998) (PubMed).
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Drak2 is upstream of p70S6 kinase: its implication in cytokine-induced islet apoptosis, diabetes, and islet transplantation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 8, pp. 4762-70, (2009) (PubMed).
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- 抗原
- DRAK2 (STK17B) (serine/threonine Kinase 17b (STK17B))
- 别名
- DRAK2 (STK17B 产品)
- 别名
- zgc:65989 antibody, STK17B antibody, DRAK2 antibody, Drak2 antibody, 3110009A03Rik antibody, AI120141 antibody, serine/threonine kinase 17b (apoptosis-inducing) antibody, serine/threonine kinase 17b antibody, stk17b antibody, STK17B antibody, Stk17b antibody
- 背景
- DRAK2 is a novel serine/threonine kinase that induces apoptosis via catalytic activity. DRAKs present high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases. DRAK2 is located in nucleus, and the messenger RNA is ubiquitously expressed in human tissues.
- 分子量
- 42344
- NCBI登录号
- NP_004217
- UniProt
- O94768
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