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- 抗原 See all ULK1 抗体
- ULK1 (Unc-51 Like Kinase 1 (ULK1))
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抗原表位
- pSer317
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ULK1 antibody is un-conjugated
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应用范围
- Dot Blot (DB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This ULK1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S317 of human ULK1.
- 克隆位点
- RB40755
- 亚型
- Ig Fraction
- Top Product
- Discover our top product ULK1 Primary Antibody
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- 应用备注
- DB: 1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy." in: Autophagy, Vol. 5, Issue 5, pp. 649-62, (2009) (PubMed).
: "ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy." in: The Journal of biological chemistry, Vol. 284, Issue 18, pp. 12297-305, (2009) (PubMed).
: "ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery." in: Molecular biology of the cell, Vol. 20, Issue 7, pp. 1992-2003, (2009) (PubMed).
: "Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy." in: Molecular biology of the cell, Vol. 20, Issue 7, pp. 1981-91, (2009) (PubMed).
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A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy." in: Autophagy, Vol. 5, Issue 5, pp. 649-62, (2009) (PubMed).
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- 抗原
- ULK1 (Unc-51 Like Kinase 1 (ULK1))
- 别名
- ULK1 (ULK1 产品)
- 背景
- Involved in autophagy. Required for autophagosome formation (By similarity). Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13/KIAA0652 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex (By similarity). Phosphorylates ATG13/KIAA0652. Involved in axon growth (By similarity). Plays an essential role in neurite extension of cerebellar granule cells (By similarity).
- 分子量
- 112631
- NCBI登录号
- NP_003556
- UniProt
- O75385
- 途径
- Regulation of Cell Size, Autophagy
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