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UGT2B28 抗体 (AA 218-246)

UGT2B28 适用: 人 WB 宿主: 兔 Polyclonal RB41660 unconjugated
产品编号 ABIN1881976
发货至: 中国
  • 抗原 See all UGT2B28 抗体
    UGT2B28 (UDP Glucuronosyltransferase 2 Family, Polypeptide B28 (UGT2B28))
    抗原表位
    AA 218-246
    适用
    宿主
    • 2
    克隆类型
    • 2
    多克隆
    标记
    • 2
    This UGT2B28 antibody is un-conjugated
    应用范围
    • 1
    • 1
    Western Blotting (WB)
    预测反应
    Pr
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This UGT2B28 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-246 amino acids from the Central region of human UGT2B28.
    克隆位点
    RB41660
    亚型
    Ig Fraction
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Setlur, Chen, Hossain, Ha, Van Doren, Stenzel, Steiner, Oldridge, Kitabayashi, Banerjee, Chen, Schäfer, Horninger, Lee, Rubin, Klocker, Demichelis: "Genetic variation of genes involved in dihydrotestosterone metabolism and the risk of prostate cancer." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 1, pp. 229-39, (2010) (PubMed).

    Ménard, Eap, Harvey, Guillemette, Lévesque: "Copy-number variations (CNVs) of the human sex steroid metabolizing genes UGT2B17 and UGT2B28 and their associations with a UGT2B15 functional polymorphism." in: Human mutation, Vol. 30, Issue 9, pp. 1310-9, (2009) (PubMed).

    Ross, Katzov-Eckert, Dubé, Brooks, Rassekh, Barhdadi, Feroz-Zada, Visscher, Brown, Rieder, Rogers, Phillips, Carleton, Hayden: "Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy." in: Nature genetics, Vol. 41, Issue 12, pp. 1345-9, (2009) (PubMed).

    Lévesque, Turgeon, Carrier, Montminy, Beaulieu, Bélanger: "Isolation and characterization of the UGT2B28 cDNA encoding a novel human steroid conjugating UDP-glucuronosyltransferase." in: Biochemistry, Vol. 40, Issue 13, pp. 3869-81, (2001) (PubMed).

  • 抗原
    UGT2B28 (UDP Glucuronosyltransferase 2 Family, Polypeptide B28 (UGT2B28))
    别名
    UGT2B28 (UGT2B28 产品)
    别名
    UDP glucuronosyltransferase family 2 member B28 antibody, UGT2B28 antibody
    背景
    UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme has glucuronidating capacity with steroid substrates such as 5-beta-androstane 3-alpha,17-beta-diol, estradiol, ADT, eugenol and bile acids. Only isoform 1 seems to be active.
    分子量
    60906
    NCBI登录号
    NP_001193933, NP_444267
    UniProt
    Q9BY64
    途径
    Steroid Hormone Biosynthesis
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