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UBE2L3 抗体 (C-Term)

UBE2L3 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB41666 unconjugated
产品编号 ABIN1881966
发货至: 中国
  • 抗原 See all UBE2L3 抗体
    UBE2L3 (Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3))
    抗原表位
    • 15
    • 8
    • 8
    • 7
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 106-135, C-Term
    适用
    • 57
    • 13
    • 10
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    人, 小鼠, 大鼠
    宿主
    • 55
    • 1
    • 1
    克隆类型
    • 55
    • 2
    多克隆
    标记
    • 29
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UBE2L3 antibody is un-conjugated
    应用范围
    • 52
    • 27
    • 20
    • 13
    • 13
    • 12
    • 8
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    B
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This UBE2L3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-135 amino acids from the C-terminal region of human UBE2L3.
    克隆位点
    RB41666
    亚型
    Ig Fraction
    Top Product
    Discover our top product UBE2L3 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:25
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Amidon, Hawley: "Oral bioperformance and 21st century dissolution." in: Molecular pharmaceutics, Vol. 7, Issue 5, pp. 1361, (2013) (PubMed).

    Fransen, Visschedijk, van Sommeren, Fu, Franke, Festen, Stokkers, van Bodegraven, Crusius, Hommes, Zanen, de Jong, Wijmenga, van Diemen, Weersma: "Analysis of SNPs with an effect on gene expression identifies UBE2L3 and BCL3 as potential new risk genes for Crohn's disease." in: Human molecular genetics, Vol. 19, Issue 17, pp. 3482-8, (2010) (PubMed).

    Dubois, Trynka, Franke, Hunt, Romanos, Curtotti, Zhernakova, Heap, Adány, Aromaa, Bardella, van den Berg, Bockett, de la Concha, Dema, Fehrmann, Fernández-Arquero, Fiatal, Grandone, Green, Groen et al.: "Multiple common variants for celiac disease influencing immune gene expression. ..." in: Nature genetics, Vol. 42, Issue 4, pp. 295-302, (2010) (PubMed).

    Kamatani, Matsuda, Okada, Kubo, Hosono, Daigo, Nakamura, Kamatani: "Genome-wide association study of hematological and biochemical traits in a Japanese population." in: Nature genetics, Vol. 42, Issue 3, pp. 210-5, (2010) (PubMed).

    Han, Zheng, Cui, Sun, Ye, Hu, Xu, Cai, Huang, Zhao, Xie, Fang, Lu, Xu, Li, Pan, Deng, Zeng, Ye, Zhang, Wang, Hao, Ma, Zuo, Zhou, Du, Cheng, Yang, Shen, Li, Sheng, Zuo, Zhu, Gao, Zhang, Guo, Li et al.: "Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus...." in: Nature genetics, Vol. 41, Issue 11, pp. 1234-7, (2009) (PubMed).

  • 抗原
    UBE2L3 (Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3))
    别名
    UBE2L3 (UBE2L3 产品)
    背景
    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Several alternatively spliced transcript variants have been found for this gene.
    分子量
    17862
    NCBI登录号
    NP_001243284, NP_001243285, NP_003338
    UniProt
    P68036
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