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TXNIP 抗体 (N-Term)

Name: TXNIP 抗体 (N-Term)
SKU: ABIN1881962
Availability: OutOfStock

TXNIP 适用: 人 WB 宿主: 兔 Polyclonal RB41554 unconjugated

All lanes : Anti-TXNIP Antibody (N-term) at 1:1000 dilution Lane 1: LNCaP whole cell lysate Lane 2: MCF-7 whole cell lysate Lysates/proteins at 20 μg per lane. (TXNIP 抗体 (N-Term))

TXNIP Antibody (N-term) (ABIN1881962 and ABIN2838827) western blot analysis in NCI- cell line lysates (35 μg/lane). (TXNIP 抗体 (N-Term))

2 images

(4 references)

产品编号 ABIN1881962

发货至: 中国

Datasheet as PDF

抗原 See all TXNIP 抗体

TXNIP (Thioredoxin Interacting Protein (TXNIP))
抗原表位
16

13

8

8

5

5

3

1

1

1

1

1

1

1

1

1

1
AA 1-30, N-Term
适用
67

48

33

5

4

4

3

3

2

2

1

1
人
宿主
76

5
兔
Compatible Secondaries
克隆类型
68

13
多克隆
标记
30

8

7

6

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
This TXNIP antibody is un-conjugated
应用范围
57

32

15

14

14

8

8

5

4

3

3

1

1
Western Blotting (WB)

预测反应

M, Rat

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This TXNIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TXNIP.

克隆位点

RB41554

亚型

Ig Fraction

Top Product

Discover our top product TXNIP Primary Antibody
anti-Thioredoxin Interacting Protein (TXNIP) (AA 30-381) antibody
TXNIP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (AA 1-166) antibody
TXNIP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (AA 32-367) antibody
TXNIP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (C-Term) antibody
TXNIP 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 绵羊 WB 宿主: 兔 Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (AA 116-145) antibody
TXNIP 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB30652 unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (Internal Region) antibody
TXNIP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (AA 101-200) antibody
TXNIP 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (C-Term) antibody
TXNIP 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 绵羊, 猴, Bat, Pig, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (AA 299-381) antibody
TXNIP 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (AA 121-170) antibody
TXNIP 适用: 人, 犬, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000. WB: 1:1000

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Zhuo, Niu, Chen, Xin, Guo, Mao: "Vitamin D3 up-regulated protein 1(VDUP1) is regulated by FOXO3A and miR-17-5p at the transcriptional and post-transcriptional levels, respectively, in senescent fibroblasts." in: The Journal of biological chemistry, Vol. 285, Issue 41, pp. 31491-501, (2010) (PubMed).

Kwon, Won, Suh, Jeon, Shao, Yoon, Chung, Kim, Kim, Nam, Yoon, Kim, Kim, Kim, Kim, Kim, Choi: "Vitamin D3 upregulated protein 1 suppresses TNF-?-induced NF-?B activation in hepatocarcinogenesis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 7, pp. 3980-9, (2010) (PubMed).

Yu, Chai, He, Hagen, Luo: "Thioredoxin-interacting protein (Txnip) gene expression: sensing oxidative phosphorylation status and glycolytic rate." in: The Journal of biological chemistry, Vol. 285, Issue 33, pp. 25822-30, (2010) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).
抗原

TXNIP (Thioredoxin Interacting Protein (TXNIP))

别名

TXNIP (TXNIP 产品)

别名

EST01027 antibody, HHCPA78 antibody, THIF antibody, VDUP1 antibody, Gm348 antibody, Trf3 antibody, TBP2 antibody, TRF3 antibody, 1200008J08Rik antibody, AA682105 antibody, Hyplip1 antibody, Tbp-2 antibody, Vdup1 antibody, sb:cb368 antibody, txnip antibody, thioredoxin interacting protein antibody, TATA box binding protein like 2 antibody, TATA-box binding protein like 2 antibody, thioredoxin interacting protein L homeolog antibody, thioredoxin interacting protein a antibody, TXNIP antibody, Tbpl2 antibody, TBPL2 antibody, Txnip antibody, txnip.L antibody, txnip antibody, txnipa antibody

背景

TXNIP may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells.

分子量

43661

NCBI登录号

NP_006463

UniProt

Q9H3M7

途径

Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome