This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This TTC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 372-401 amino acids from the C-terminal region of human TTC5.
Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2 (By similarity).