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Tuberin 抗体 (N-Term)

TSC2 适用: 人 WB 宿主: 兔 Polyclonal RB41161 unconjugated
产品编号 ABIN1881945
发货至: 中国
  • 抗原 See all Tuberin (TSC2) 抗体
    Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
    抗原表位
    • 33
    • 21
    • 19
    • 19
    • 16
    • 16
    • 15
    • 15
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    • 12
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 479-508, N-Term
    适用
    • 283
    • 186
    • 122
    • 8
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 375
    • 12
    克隆类型
    • 367
    • 20
    多克隆
    标记
    • 136
    • 34
    • 33
    • 31
    • 24
    • 23
    • 7
    • 7
    • 7
    • 7
    • 7
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    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 1
    This Tuberin antibody is un-conjugated
    应用范围
    • 209
    • 173
    • 122
    • 81
    • 80
    • 60
    • 37
    • 31
    • 20
    • 12
    • 8
    • 7
    • 6
    • 5
    • 2
    Western Blotting (WB)
    预测反应
    M, Rat
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This TSC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 479-508 amino acids from the N-terminal region of human TSC2.
    克隆位点
    RB41161
    亚型
    Ig Fraction
    Top Product
    Discover our top product TSC2 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Dántola, Denofrio, Zurbano, Gimenez, Ogilby, Lorente, Thomas: "Mechanism of photooxidation of folic acid sensitized by unconjugated pterins." in: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, Vol. 9, Issue 12, pp. 1604-12, (2010) (PubMed).

    Larson, Liu, Stevens, Li, Li, Evers, Gao: "Tuberous sclerosis complex 2 (TSC2) regulates cell migration and polarity through activation of CDC42 and RAC1." in: The Journal of biological chemistry, Vol. 285, Issue 32, pp. 24987-98, (2010) (PubMed).

    Liu, Wu, Chen, Ter-Minassian, Asomaning, Zhai, Wang, Su, Heist, Kulke, Lin, Liu, Christiani: "A Large-scale genetic association study of esophageal adenocarcinoma risk." in: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, (2010) (PubMed).

  • 抗原
    Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
    别名
    TSC2 (TSC2 产品)
    别名
    TSC2 antibody, fc16b02 antibody, tuberin antibody, wu:fc16b02 antibody, LAM antibody, TSC4 antibody, Nafld antibody, Tcs2 antibody, Rc antibody, TSC complex subunit 2 antibody, tuberin antibody, hypothetical protein antibody, tuberous sclerosis 2 antibody, TSC2 antibody, LOC5569538 antibody, tsc2 antibody, PGTG_00159 antibody, Tsc2 antibody
    背景
    Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.
    分子量
    200608
    NCBI登录号
    NP_000539, NP_001070651, NP_001107854
    UniProt
    P49815
    途径
    RTK signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus
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