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TSC1 抗体 (pSer1130)

TSC1 适用: 小鼠 DB 宿主: 兔 Polyclonal RB41227 unconjugated
产品编号 ABIN1881911
发货至: 中国
  • 抗原 See all TSC1 抗体
    TSC1 (Tuberous Sclerosis 1 (TSC1))
    抗原表位
    • 24
    • 16
    • 16
    • 16
    • 15
    • 15
    • 13
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer1130
    适用
    • 187
    • 137
    • 52
    • 24
    • 18
    • 2
    • 1
    • 1
    小鼠
    宿主
    • 300
    • 16
    • 1
    • 1
    克隆类型
    • 302
    • 16
    多克隆
    标记
    • 112
    • 37
    • 36
    • 36
    • 32
    • 32
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    This TSC1 antibody is un-conjugated
    应用范围
    • 230
    • 207
    • 91
    • 28
    • 26
    • 26
    • 16
    • 13
    • 9
    • 6
    • 6
    • 4
    • 3
    • 1
    Dot Blot (DB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This mouse TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1130 of mouse TSC1.
    克隆位点
    RB41227
    亚型
    Ig Fraction
    Top Product
    Discover our top product TSC1 Primary Antibody
  • 应用备注
    DB: 1:500
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Akpa, Oyejola: "Modeling the transmission dynamics of HIV/AIDS epidemics: an introduction and a review." in: Journal of infection in developing countries, Vol. 4, Issue 10, pp. 597-608, (2010) (PubMed).

    Kladney, Cardiff, Kwiatkowski, Chiang, Weber, Arbeit, Lu: "Tuberous sclerosis complex 1: an epithelial tumor suppressor essential to prevent spontaneous prostate cancer in aged mice." in: Cancer research, Vol. 70, Issue 21, pp. 8937-47, (2010) (PubMed).

  • 抗原
    TSC1 (Tuberous Sclerosis 1 (TSC1))
    别名
    TSC1 (TSC1 产品)
    别名
    LAM antibody, TSC antibody, hamartin antibody, mKIAA0243 antibody, tsc1 antibody, wu:fc38b04 antibody, fa99f04 antibody, wu:fa99f04 antibody, zgc:63657 antibody, TSC complex subunit 1 antibody, tuberous sclerosis 1 antibody, TSC complex subunit 1b antibody, TSC complex subunit 1a antibody, TSC1 antibody, Tsc1 antibody, tsc1b antibody, tsc1 antibody, tsc1a antibody
    背景
    In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
    分子量
    128746
    NCBI登录号
    NP_075025
    UniProt
    Q9EP53
    途径
    RTK signaling, AMPK Signaling, Regulation of Cell Size, Tube Formation
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