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- 抗原 See all TSC1 抗体
- TSC1 (Tuberous Sclerosis 1 (TSC1))
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抗原表位
- pTyr297
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TSC1 antibody is un-conjugated
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应用范围
- Dot Blot (DB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This rat TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y297 of rat TSC1.
- 克隆位点
- RB41272
- 亚型
- Ig Fraction
- Top Product
- Discover our top product TSC1 Primary Antibody
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- 应用备注
- DB: 1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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Hamartin-Hsp70 interaction is necessary for Akt-dependent tuberin phosphorylation during heat shock." in: Bioscience, biotechnology, and biochemistry, Vol. 73, Issue 11, pp. 2488-93, (2009) (PubMed).
: "Tuberous sclerosis complex activity is required to control neuronal stress responses in an mTOR-dependent manner." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 18, pp. 5926-37, (2009) (PubMed).
: "The variation of AkT/TSC1-TSC1/mTOR signal pathway in hepatocytes after partial hepatectomy in rats." in: Experimental and molecular pathology, Vol. 86, Issue 2, pp. 101-7, (2009) (PubMed).
: "N-terminal hamartin-binding and C-terminal GAP domain of tuberin can separate in vivo." in: Biochemical and biophysical research communications, Vol. 356, Issue 3, pp. 693-8, (2007) (PubMed).
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Hamartin-Hsp70 interaction is necessary for Akt-dependent tuberin phosphorylation during heat shock." in: Bioscience, biotechnology, and biochemistry, Vol. 73, Issue 11, pp. 2488-93, (2009) (PubMed).
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- 抗原
- TSC1 (Tuberous Sclerosis 1 (TSC1))
- 别名
- TSC1 (TSC1 产品)
- 别名
- LAM antibody, TSC antibody, hamartin antibody, mKIAA0243 antibody, tsc1 antibody, wu:fc38b04 antibody, fa99f04 antibody, wu:fa99f04 antibody, zgc:63657 antibody, TSC complex subunit 1 antibody, tuberous sclerosis 1 antibody, TSC complex subunit 1b antibody, TSC complex subunit 1a antibody, TSC1 antibody, Tsc1 antibody, tsc1b antibody, tsc1 antibody, tsc1a antibody
- 背景
- In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
- 分子量
- 129022
- NCBI登录号
- NP_068626
- UniProt
- Q9Z136
- 途径
- RTK signaling, AMPK Signaling, Regulation of Cell Size, Tube Formation
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