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- 抗原 See all TNNC2 抗体
- TNNC2 (Fast Skeletal Troponin C (TNNC2))
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抗原表位
- AA 97-126, C-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TNNC2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This TNNC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 97-126 amino acids from the C-terminal region of human TNNC2.
- 克隆位点
- RB32470
- 亚型
- Ig Fraction
- Top Product
- Discover our top product TNNC2 Primary Antibody
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- 应用备注
- WB: 1:1000. WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).
: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).
: "Mutations in fast skeletal troponin I, troponin T, and beta-tropomyosin that cause distal arthrogryposis all increase contractile function." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 21, Issue 3, pp. 896-905, (2007) (PubMed).
: "The DNA sequence and comparative analysis of human chromosome 20. ..." in: Nature, Vol. 414, Issue 6866, pp. 865-71, (2002) (PubMed).
: "Crystal structure of troponin C in complex with troponin I fragment at 2.3-A resolution." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 9, pp. 4847-52, (1998) (PubMed).
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Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).
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- 抗原
- TNNC2 (Fast Skeletal Troponin C (TNNC2))
- 别名
- TNNC2 (TNNC2 产品)
- 别名
- Tncs antibody, STNC antibody, tnnc antibody, wu:fb39a12 antibody, tnnc2 antibody, troponin C2, fast skeletal type antibody, troponin C2, fast antibody, troponin C type 2 (fast) antibody, fast skeletal troponin C beta antibody, troponin C type 2 (fast) L homeolog antibody, TNNC2 antibody, Tnnc2 antibody, tnnc2 antibody, tnnc2.L antibody
- 背景
- Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn-C subunit.
- 分子量
- 18122
- NCBI登录号
- NP_003270
- UniProt
- P02585
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