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TNNC2 抗体 (C-Term)

TNNC2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB32470 unconjugated
产品编号 ABIN1881894
发货至: 中国
  • 抗原 See all TNNC2 抗体
    TNNC2 (Fast Skeletal Troponin C (TNNC2))
    抗原表位
    • 13
    • 6
    • 5
    • 2
    • 1
    • 1
    AA 97-126, C-Term
    适用
    • 33
    • 20
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 32
    • 1
    克隆类型
    • 33
    多克隆
    标记
    • 13
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TNNC2 antibody is un-conjugated
    应用范围
    • 26
    • 20
    • 7
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This TNNC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 97-126 amino acids from the C-terminal region of human TNNC2.
    克隆位点
    RB32470
    亚型
    Ig Fraction
    Top Product
    Discover our top product TNNC2 Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

    Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).

    Robinson, Lipscomb, Preston, Altin, Watkins, Ashley, Redwood: "Mutations in fast skeletal troponin I, troponin T, and beta-tropomyosin that cause distal arthrogryposis all increase contractile function." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 21, Issue 3, pp. 896-905, (2007) (PubMed).

    Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: "The DNA sequence and comparative analysis of human chromosome 20. ..." in: Nature, Vol. 414, Issue 6866, pp. 865-71, (2002) (PubMed).

    Vassylyev, Takeda, Wakatsuki, Maeda, Maéda: "Crystal structure of troponin C in complex with troponin I fragment at 2.3-A resolution." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 9, pp. 4847-52, (1998) (PubMed).

  • 抗原
    TNNC2 (Fast Skeletal Troponin C (TNNC2))
    别名
    TNNC2 (TNNC2 产品)
    别名
    Tncs antibody, STNC antibody, tnnc antibody, wu:fb39a12 antibody, tnnc2 antibody, troponin C2, fast skeletal type antibody, troponin C2, fast antibody, troponin C type 2 (fast) antibody, fast skeletal troponin C beta antibody, troponin C type 2 (fast) L homeolog antibody, TNNC2 antibody, Tnnc2 antibody, tnnc2 antibody, tnnc2.L antibody
    背景
    Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn-C subunit.
    分子量
    18122
    NCBI登录号
    NP_003270
    UniProt
    P02585
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