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- 抗原 See all TIPIN 抗体
- TIPIN (TIMELESS Interacting Protein (TIPIN))
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抗原表位
- AA 227-254, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TIPIN antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This TIPIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-254 amino acids from the N-terminal region of human TIPIN.
- 克隆位点
- RB40607
- 亚型
- Ig Fraction
- Top Product
- Discover our top product TIPIN Primary Antibody
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress." in: The Journal of biological chemistry, Vol. 285, Issue 22, pp. 16562-71, (2010) (PubMed).
: "Human Timeless and Tipin stabilize replication forks and facilitate sister-chromatid cohesion." in: Journal of cell science, Vol. 123, Issue Pt 5, pp. 660-70, (2010) (PubMed).
: "Mammalian TIMELESS and Tipin are evolutionarily conserved replication fork-associated factors." in: Journal of molecular biology, Vol. 366, Issue 1, pp. 36-52, (2007) (PubMed).
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Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress." in: The Journal of biological chemistry, Vol. 285, Issue 22, pp. 16562-71, (2010) (PubMed).
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- 抗原
- TIPIN (TIMELESS Interacting Protein (TIPIN))
- 别名
- TIPIN (TIPIN 产品)
- 别名
- 1110005A05Rik antibody, 1110018P21Rik antibody, RGD1564084 antibody, MGC82649 antibody, zgc:91928 antibody, tipin antibody, TIMELESS interacting protein antibody, timeless interacting protein antibody, timeless interacting protein S homeolog antibody, timeless interacting protein L homeolog antibody, TIPIN antibody, Tipin antibody, tipin.S antibody, tipin antibody, tipin.L antibody
- 背景
- Required for normal progression of S-phase. Important for cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light.
- 分子量
- 34555
- NCBI登录号
- NP_060328
- UniProt
- Q9BVW5
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