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- 抗原 See all TFEC 抗体
- TFEC (Transcription Factor EC (TFEC))
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抗原表位
- AA 179-205
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TFEC antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 预测反应
- C, M, Rat
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This TFEC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-205 amino acids from the Central region of human TFEC.
- 克隆位点
- RB40605
- 亚型
- Ig Fraction
- Top Product
- Discover our top product TFEC Primary Antibody
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C collaborate to activate the tartrate-resistant acid phosphatase promoter." in: Journal of leukocyte biology, Vol. 71, Issue 2, pp. 304-10, (2002) (PubMed).
: "TFEC can function as a transcriptional activator of the nonmuscle myosin II heavy chain-A gene in transfected cells." in: Biochemistry, Vol. 40, Issue 30, pp. 8887-97, (2001) (PubMed).
: "The bHLH-Zip transcription factor Tfeb is essential for placental vascularization." in: Development (Cambridge, England), Vol. 125, Issue 23, pp. 4607-16, (1999) (PubMed).
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The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C collaborate to activate the tartrate-resistant acid phosphatase promoter." in: Journal of leukocyte biology, Vol. 71, Issue 2, pp. 304-10, (2002) (PubMed).
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- 抗原
- TFEC (Transcription Factor EC (TFEC))
- 别名
- TFEC (TFEC 产品)
- 别名
- si:ch211-238e6.5 antibody, TFEC antibody, TCFEC antibody, TFE-C antibody, TFEC-L antibody, TFECL antibody, bHLHe34 antibody, hTFEC-L antibody, BB107417 antibody, Tcfec antibody, transcription factor EC antibody, tfec antibody, TFEC antibody, Tfec antibody
- 背景
- Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence). Binds to element F in an E-box sequence-specific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter (By similarity). Collaborates with MITF in target gene activation (By similarity). Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence (By similarity). Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer (By similarity). Binds DNA in a homo-or heterodimeric form.
- 分子量
- 38788
- NCBI登录号
- NP_001018068, NP_001231512, NP_036384
- UniProt
- O14948
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