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- 抗原 See all SPTLC2 抗体
- SPTLC2 (serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2))
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抗原表位
- AA 372-401
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SPTLC2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 预测反应
- M, Rat
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This SPTLC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 372-401 amino acids from the Central region of human SPTLC2.
- 克隆位点
- RB42738
- 亚型
- Ig Fraction
- Top Product
- Discover our top product SPTLC2 Primary Antibody
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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Mutations in the SPTLC2 subunit of serine palmitoyltransferase cause hereditary sensory and autonomic neuropathy type I." in: American journal of human genetics, Vol. 87, Issue 4, pp. 513-22, (2010) (PubMed).
: "Identification of small subunits of mammalian serine palmitoyltransferase that confer distinct acyl-CoA substrate specificities." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 20, pp. 8186-91, (2009) (PubMed).
: "The essential nature of sphingolipids in plants as revealed by the functional identification and characterization of the Arabidopsis LCB1 subunit of serine palmitoyltransferase." in: The Plant cell, Vol. 18, Issue 12, pp. 3576-93, (2007) (PubMed).
: "Is the mammalian serine palmitoyltransferase a high-molecular-mass complex?" in: The Biochemical journal, Vol. 405, Issue 1, pp. 157-64, (2007) (PubMed).
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Mutations in the SPTLC2 subunit of serine palmitoyltransferase cause hereditary sensory and autonomic neuropathy type I." in: American journal of human genetics, Vol. 87, Issue 4, pp. 513-22, (2010) (PubMed).
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- 抗原
- SPTLC2 (serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2))
- 别名
- SPTLC2 (SPTLC2 产品)
- 别名
- HSN1C antibody, LCB2 antibody, LCB2A antibody, NSAN1C antibody, SPT2 antibody, hLCB2a antibody, sptlc2 antibody, zgc:110661 antibody, AI173915 antibody, mKIAA0526 antibody, Pomt2 antibody, LCB2a antibody, SPTLC2 antibody, serine palmitoyltransferase long chain base subunit 2 antibody, serine palmitoyltransferase 2 antibody, serine palmitoyltransferase, long chain base subunit 2 S homeolog antibody, serine palmitoyltransferase, long chain base subunit 2a antibody, serine palmitoyltransferase, long chain base subunit 2 antibody, SPTLC2 antibody, LOC100446763 antibody, sptlc2 antibody, sptlc2.S antibody, sptlc2a antibody, Sptlc2 antibody
- 背景
- This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. Alternatively spliced variants encoding different isoforms have been identified.
- 分子量
- 62924
- NCBI登录号
- NP_004854
- UniProt
- O15270
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