This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This SETD1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 927-956 amino acids from the Central region of human SETD1A.
SET1A is a component of a histone methyltransferase (HMT) complex that produces mono-, di-, and trimethylated histone H3 at Lys4. The complex is the analog of the S. cerevisiae Set1/COMPASS complex (Lee and Skalnik, 2005 [PubMed 16253997]). Also see SET1B (MIM 611055).