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- 抗原 See all SEMA7A 抗体
- SEMA7A (Semaphorin 7A, GPI Membrane Anchor (John Milton Hagen Blood Group) (SEMA7A))
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抗原表位
- AA 178-202, N-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SEMA7A antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This SEMA7A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-202 amino acids from the N-terminal region of human SEMA7A.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product SEMA7A Primary Antibody
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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Endogenous Semaphorin-7A Impedes Human Lung Fibroblast Differentiation." in: PLoS ONE, Vol. 12, Issue 1, pp. e0170207, (2017) (PubMed).
: "The molecular diversity of Sema7A, the semaphorin that carries the JMH blood group antigens." in: Transfusion, Vol. 47, Issue 1, pp. 133-46, (2007) (PubMed).
: "Molecular cloning of a glycosylphosphatidylinositol-anchored molecule CDw108." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 7, pp. 4094-100, (1999) (PubMed).
: "Characterization of the human leukocyte GPI-anchored glycoprotein CDw108 and its relation to other similar molecules." in: Immunobiology, Vol. 200, Issue 2, pp. 234-45, (1999) (PubMed).
: "New eukaryotic semaphorins with close homology to semaphorins of DNA viruses." in: Genomics, Vol. 51, Issue 3, pp. 340-50, (1998) (PubMed).
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Endogenous Semaphorin-7A Impedes Human Lung Fibroblast Differentiation." in: PLoS ONE, Vol. 12, Issue 1, pp. e0170207, (2017) (PubMed).
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- 抗原
- SEMA7A (Semaphorin 7A, GPI Membrane Anchor (John Milton Hagen Blood Group) (SEMA7A))
- 别名
- SEMA7A (SEMA7A 产品)
- 别名
- 2900057C09Rik antibody, CDw108 antibody, H-Sema-L antibody, M-Sema-L antibody, Semal antibody, CD108 antibody, H-SEMA-K1 antibody, JMH antibody, SEMAK1 antibody, SEMAL antibody, sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A antibody, semaphorin 7A (John Milton Hagen blood group) antibody, Sema7a antibody, SEMA7A antibody
- 背景
- Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.
- 分子量
- 74824
- NCBI登录号
- NP_001139501, NP_001139502, NP_003603
- UniProt
- O75326
- 途径
- Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
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