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- 抗原 See all RLIM 抗体
- RLIM (Ring Finger Protein, LIM Domain Interacting (RLIM))
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抗原表位
- AA 199-227
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RLIM antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This RLIM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 199-227 amino acids from the Central region of human RLIM.
- 克隆位点
- RB42228
- 亚型
- Ig Fraction
- Top Product
- Discover our top product RLIM Primary Antibody
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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RNF12 is an X-Encoded dose-dependent activator of X chromosome inactivation." in: Cell, Vol. 139, Issue 5, pp. 999-1011, (2009) (PubMed).
: "Ubiquitin Ligase RLIM Modulates Telomere Length Homeostasis through a Proteolysis of TRF1." in: The Journal of biological chemistry, Vol. 284, Issue 13, pp. 8557-66, (2009) (PubMed).
: "Phosphopeptide enrichment by aliphatic hydroxy acid-modified metal oxide chromatography for nano-LC-MS/MS in proteomics applications." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 6, pp. 1103-9, (2007) (PubMed).
: "Selective degradation of excess Ldb1 by Rnf12/RLIM confers proper Ldb1 expression levels and Xlim-1/Ldb1 stoichiometry in Xenopus organizer functions." in: Development (Cambridge, England), Vol. 130, Issue 17, pp. 4161-75, (2003) (PubMed).
: "Ubiquitination-dependent cofactor exchange on LIM homeodomain transcription factors." in: Nature, Vol. 416, Issue 6876, pp. 99-103, (2002) (PubMed).
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RNF12 is an X-Encoded dose-dependent activator of X chromosome inactivation." in: Cell, Vol. 139, Issue 5, pp. 999-1011, (2009) (PubMed).
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- 抗原
- RLIM (Ring Finger Protein, LIM Domain Interacting (RLIM))
- 别名
- RLIM (RLIM 产品)
- 别名
- NY-REN-43 antibody, RNF12 antibody, AL022832 antibody, AW743871 antibody, Ha1r antibody, Rnf12 antibody, R-LIM antibody, ring finger protein, LIM domain interacting antibody, XRnf12C protein antibody, RLIM antibody, Rlim antibody, xrnf12c antibody, rlim antibody
- 背景
- The protein encoded by this gene is a RING-H2 zinc finger protein. It has been shown to be an E3 ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Multiple alternatively spliced variants, encoding the same protein, have been identified.
- 分子量
- 68549
- NCBI登录号
- NP_057204, NP_899196
- UniProt
- Q9NVW2
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