This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This RBPMS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-193 amino acids from the C-terminal region of human RBPMS.
HERMES antibody, 2010300K22Rik antibody, 2700019M19Rik antibody, AU017537 antibody, hermes antibody, RGD1561067 antibody, si:cabz01079824.1 antibody, RNA binding protein with multiple splicing antibody, RNA binding protein gene with multiple splicing antibody, RNA binding protein with multiple splicing L homeolog antibody, RBPMS antibody, Rbpms antibody, rbpms.L antibody, rbpms antibody
背景
Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly(A) RNA.