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Poliovirus Receptor 抗体 (C-Term)

PVR 适用: 人 WB 宿主: 兔 Polyclonal RB41981 unconjugated
产品编号 ABIN1881709
发货至: 中国
  • 抗原 See all Poliovirus Receptor (PVR) 抗体
    Poliovirus Receptor (PVR)
    抗原表位
    • 13
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 314-342, C-Term
    适用
    • 51
    • 11
    • 5
    • 1
    宿主
    • 43
    • 9
    • 5
    克隆类型
    • 40
    • 16
    • 1
    多克隆
    标记
    • 30
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Poliovirus Receptor antibody is un-conjugated
    应用范围
    • 34
    • 25
    • 14
    • 11
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This PVR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-342 amino acids from the C-terminal region of human PVR.
    克隆位点
    RB41981
    亚型
    Ig Fraction
    Top Product
    Discover our top product PVR Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Nakai, Maniwa, Tanaka, Nishio, Yoshimura, Okita, Ohbayashi, Satoh, Ogita, Takai, Hayashi: "Overexpression of Necl-5 correlates with unfavorable prognosis in patients with lung adenocarcinoma." in: Cancer science, Vol. 101, Issue 5, pp. 1326-30, (2010) (PubMed).

    Carlsten, Norell, Bryceson, Poschke, Schedvins, Ljunggren, Kiessling, Malmberg: "Primary human tumor cells expressing CD155 impair tumor targeting by down-regulating DNAM-1 on NK cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 8, pp. 4921-30, (2009) (PubMed).

    Kindberg, Ax, Fiore, Svensson: "Ala67Thr mutation in the poliovirus receptor CD155 is a potential risk factor for vaccine and wild-type paralytic poliomyelitis." in: Journal of medical virology, Vol. 81, Issue 5, pp. 933-6, (2009) (PubMed).

  • 抗原
    Poliovirus Receptor (PVR)
    别名
    PVR (PVR 产品)
    别名
    PVR antibody, CD155 antibody, HVED antibody, NECL5 antibody, Necl-5 antibody, PVS antibody, TAGE4 antibody, 3830421F03Rik antibody, D7Ertd458e antibody, Taa1 antibody, Tage4 antibody, mE4 antibody, necl-5 antibody, poliovirus receptor antibody, PVR antibody, Pvr antibody
    背景
    The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.
    分子量
    45303
    NCBI登录号
    NP_001129240, NP_001129241, NP_001129242, NP_006496
    UniProt
    P15151
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome
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