我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

PROX1 抗体 (AA 175-206)

Name: PROX1 抗体 (AA 175-206)
SKU: ABIN1881686
Availability: OutOfStock

PROX1 适用: 人 WB 宿主: 兔 Polyclonal RB15516 unconjugated

PROX-1 Antibody (ABIN1881686 and ABIN2850428) western blot analysis in SH-SY5Y cell line lysates (35 μg/lane). (PROX1 抗体 (AA 175-206))

1 image

(4 references)

产品编号 ABIN1881686

发货至: 中国

Datasheet as PDF

抗原 See all PROX1 抗体

PROX1 (Prospero Homeobox 1 (PROX1))
抗原表位
16

14

9

9

8

8

6

5

4

3

2

2

2

1

1

1

1

1

1

1
AA 175-206
适用
99

53

26

3

2

2

1

1

1

1

1

1

1

1
人
宿主
91

8
兔
Compatible Secondaries
克隆类型
90

9
多克隆
标记
47

9

8

7

6

5

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This PROX1 antibody is un-conjugated
应用范围
81

47

36

28

13

13

12

4

2

2
Western Blotting (WB)

预测反应

M

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This PROX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 175-206 amino acids from human PROX1.

克隆位点

RB15516

亚型

Ig Fraction

Top Product

Discover our top product PROX1 Primary Antibody
anti-Prospero Homeobox 1 (PROX1) (AA 638-737) antibody
PROX1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H6 unconjugated

anti-Prospero Homeobox 1 (PROX1) (AA 492-520) antibody
PROX1 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Prospero Homeobox 1 (PROX1) (AA 492-522) antibody
PROX1 适用: 人, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Prospero Homeobox 1 (PROX1) (AA 185-214) antibody
PROX1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Prospero Homeobox 1 (PROX1) (AA 638-737) antibody
PROX1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1E7 unconjugated

anti-Prospero Homeobox 1 (PROX1) (Center) antibody
PROX1 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

anti-Prospero Homeobox 1 (PROX1) (AA 444-478) antibody
PROX1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB51404 unconjugated

anti-Prospero Homeobox 1 (PROX1) (AA 1-300) antibody
PROX1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Prospero Homeobox 1 (PROX1) (AA 547-737) antibody
PROX1 适用: 人, 马, Avian WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Prospero Homeobox 1 (PROX1) antibody
PROX1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated

应用备注

WB: 1:1000

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Nagai, Li, Hatano, Toshihito, Yuge, Ito, Utsumi, Saito, Kinoshita: "Mutations and aberrant DNA methylation of the PROX1 gene in hematologic malignancies." in: Genes, chromosomes & cancer, Vol. 38, Issue 1, pp. 13-21, (2003) (PubMed).

Hong, Harvey, Noh, Schacht, Hirakawa, Detmar, Oliver: "Prox1 is a master control gene in the program specifying lymphatic endothelial cell fate." in: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 225, Issue 3, pp. 351-7, (2002) (PubMed).

Petrova, Mäkinen, Mäkelä, Saarela, Virtanen, Ferrell, Finegold, Kerjaschki, Ylä-Herttuala, Alitalo: "Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor." in: The EMBO journal, Vol. 21, Issue 17, pp. 4593-9, (2002) (PubMed).

Mouta Carreira, Nasser, di Tomaso, Padera, Boucher, Tomarev, Jain: "LYVE-1 is not restricted to the lymph vessels: expression in normal liver blood sinusoids and down-regulation in human liver cancer and cirrhosis." in: Cancer research, Vol. 61, Issue 22, pp. 8079-84, (2001) (PubMed).
抗原

PROX1 (Prospero Homeobox 1 (PROX1))

别名

PROX1 (PROX1 产品)

别名

xprox1 antibody, prospero antibody, PROX1 antibody, LOC100232600 antibody, A230003G05Rik antibody, prox1 antibody, zgc:111888 antibody, prospero homeobox 1 antibody, prospero homeobox 1 L homeolog antibody, prospero homeobox 1a antibody, PROX1 antibody, prox1.L antibody, prox1 antibody, Prox1 antibody, prox1a antibody

背景

The expression pattern of Prox1 suggests that it has a role in a variety of embryonic tissues, including lens. Prox mRNA is present in many different human tissues with lens demonstrating the highest level. Homozygous Prox1-null mice die at midgestation from multiple developmental defects, and a targeted effect on lens development has been reported. Prox1 inactivation caused abnormal cellular proliferation, downregulated expression of the cell cycle inhibitors Cdkn1b and Cdkn1c, misexpression of E-cadherin, and excessive apoptosis. Consequently, mutant lens cells failed to polarize and elongate properly, resulting in a hollow lens. Prox1 is expressed in a subpopulation of endothelial cells that by budding and sprouting give rise to the lymphatic system. Prox1 appears to be a specific and required regulator of the development of the lymphatic system. Prox1 also has been documented to be required for hepatocyte migration in the mouse. Loss of Prox1 results in a smaller liver with a reduced population of clustered hepatocytes. The homeodomain protein Prox1 regulates the egress of progenitor cells from the cell cycle in the embryonic mouse retina. Cells lacking Prox1 are less likely to stop dividing, and ectopic expression of Prox1 forces progenitor cells to exit the cell cycle. Prox1 acts as a key participant in progenitor-cell proliferation and cell-fate determination in the vertebrate retina.

分子量

83203

NCBI登录号

NP_001257545, NP_002754

UniProt

Q92786

途径

Stem Cell Maintenance, Regulation of Muscle Cell Differentiation