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Progesterone Receptor 抗体 (AA 523-550)

Name: Progesterone Receptor 抗体 (AA 523-550)
SKU: ABIN1881649
Availability: OutOfStock

PGR 适用: 人 WB 宿主: 兔 Polyclonal RB41474 unconjugated

PGR Antibody (Center) (ABIN1881649 and ABIN2838814) western blot analysis in CEM cell line lysates (35 μg/lane). (Progesterone Receptor 抗体 (AA 523-550))

1 image

(3 references)

产品编号 ABIN1881649

发货至: 中国

Datasheet as PDF

抗原 See all Progesterone Receptor (PGR) 抗体

Progesterone Receptor (PGR)
抗原表位
16

15

15

14

14

12

11

10

10

8

8

7

7

7

7

7

6

6

5

5

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 523-550
适用
245

45

42

16

15

8

6

6

5

3

3

2

1

1

1

1

1
人
宿主
187

61

1

1
兔
Compatible Secondaries
克隆类型
184

66
多克隆
标记
121

21

11

11

8

7

6

6

6

6

6

6

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1
This Progesterone Receptor antibody is un-conjugated
应用范围
177

90

60

31

28

26

26

22

18

18

17

10

6

3

2

1

1

1

1

1
Western Blotting (WB)

预测反应

M, Rat

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This PGR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 523-550 amino acids from the Central region of human PGR.

克隆位点

RB41474

亚型

Ig Fraction

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PGR 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 2E4B9 unconjugated

anti-Progesterone Receptor (PGR) antibody
PGR 适用: 人, 大鼠, 小鼠, 猴 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Progesterone Receptor (PGR) (AA 1-250) antibody
PGR 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Progesterone Receptor (PGR) (AA 501-600) antibody
PGR 适用: 人 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro), FACS 宿主: 兔 Polyclonal unconjugated

anti-Progesterone Receptor (PGR) (pSer190) antibody
PGR 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Progesterone Receptor (PGR) (AA 483-571) antibody
PGR 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal PGR-2694 unconjugated

anti-Progesterone Receptor (PGR) (pSer400) antibody
PGR 适用: 人, 猴 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Van Belle, Van Calster, Brouckaert, Vanden Bempt, Pintens, Harvey, Murray, Naume, Wiedswang, Paridaens, Moerman, Amant, Leunen, Smeets, Drijkoningen, Wildiers, Christiaens, Vergote, Van Huffel, Neven: "Qualitative assessment of the progesterone receptor and HER2 improves the Nottingham Prognostic Index up to 5 years after breast cancer diagnosis." in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 28, Issue 27, pp. 4129-34, (2010) (PubMed).

Geradts, Bean, Bentley, Barry: "The oncotype DX recurrence score is correlated with a composite index including routinely reported pathobiologic features." in: Cancer investigation, Vol. 28, Issue 9, pp. 969-77, (2010) (PubMed).

Tang, Wang, Hicks, Wang, Schiffhauer, McMahon, Yang, Shayne, Huston, Skinner, Griggs, Lyman: "A lower Allred score for progesterone receptor is strongly associated with a higher recurrence score of 21-gene assay in breast cancer." in: Cancer investigation, Vol. 28, Issue 9, pp. 978-82, (2010) (PubMed).
抗原

Progesterone Receptor (PGR)

别名

PGR (PGR 产品)

别名

NR3C3 antibody, PR antibody, 9930019P03Rik antibody, BB114106 antibody, ENSMUSG00000074510 antibody, PR-A antibody, PR-B antibody, XPR-1 antibody, pgr antibody, xpr-2 antibody, LOC443444 antibody, PGR antibody, pg antibody, pr antibody, gb:dq017620 antibody, progesterone receptor antibody, progesterone receptor L homeolog antibody, PGR antibody, Pgr antibody, pgr.L antibody, pgr antibody

背景

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform A has not been clearly determined.

分子量

98981

NCBI登录号

NP_000917, NP_001189403, NP_001258091

UniProt

P06401

途径

Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration