(4 references)-
- 抗原 See all PDE6H 抗体
- PDE6H (phosphodiesterase 6H, CGMP-Specific, Cone, gamma (PDE6H))
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抗原表位
- AA 4-33
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PDE6H antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 预测反应
- B, Rat, H
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This PDE6H antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-33 amino acids from the Central region of human PDE6H.
- 克隆位点
- RB40887
- 亚型
- Ig Fraction
- Top Product
- Discover our top product PDE6H Primary Antibody
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anti-phosphodiesterase 6H, CGMP-Specific, Cone, gamma (PDE6H) (AA 1-83) antibody
PDE6H 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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: "A substitution of G to C in the cone cGMP-phosphodiesterase gamma subunit gene found in a distinctive form of cone dystrophy." in: Ophthalmology, Vol. 112, Issue 1, pp. 159-66, (2005) (PubMed).
: "Three-dimensional structure of non-activated cGMP phosphodiesterase 6 and comparison of its image with those of activated forms." in: Journal of structural biology, Vol. 139, Issue 1, pp. 27-38, (2002) (PubMed).
: "Isolation and chromosomal localization of the human cone cGMP phosphodiesterase gamma cDNA (PDE6H)." in: Genomics, Vol. 32, Issue 1, pp. 121-4, (1996) (PubMed).
: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, (1996) (PubMed).
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: "A substitution of G to C in the cone cGMP-phosphodiesterase gamma subunit gene found in a distinctive form of cone dystrophy." in: Ophthalmology, Vol. 112, Issue 1, pp. 159-66, (2005) (PubMed).
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- 抗原
- PDE6H (phosphodiesterase 6H, CGMP-Specific, Cone, gamma (PDE6H))
- 别名
- PDE6H (PDE6H 产品)
- 别名
- ACHM6 antibody, RCD3 antibody, A930033D18Rik antibody, PDEgamma antibody, Pde6g antibody, phosphodiesterase 6H antibody, phosphodiesterase 6H, cGMP-specific, cone, gamma antibody, PDE6H antibody, Pde6h antibody
- 背景
- This gene encodes the inhibitory (or gamma) subunit of the cone-specific cGMP phosphodiesterase, which is a tetramer composed of two catalytic chains (alpha and beta), and two inhibitory chains (gamma). It is specifically expressed in the retina, and is involved in the transmission and amplification of the visual signal. Mutations in this gene are associated with retinal cone dystrophy type 3A (RCD3A).
- 分子量
- 9074
- NCBI登录号
- NP_006196
- UniProt
- Q13956
- 途径
- EGFR Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling
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