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OTX2 抗体 (C-Term)

Name: OTX2 抗体 (C-Term)
SKU: ABIN1881611
Availability: OutOfStock

OTX2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB17482 unconjugated

OTX2 Antibody (C-term) (ABIN1881611 and ABIN2845106) western blot analysis in Y79 cell line lysates (35 μg/lane). (OTX2 抗体 (C-Term))

OTX2 Antibody (C-term) (ABIN1881611 and ABIN2845106) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. (OTX2 抗体 (C-Term))

IHC (p)

2 images

(5 references)

产品编号 ABIN1881611

发货至: 中国

Datasheet as PDF

抗原 See all OTX2 抗体

OTX2 (Orthodenticle Homeobox 2 (OTX2))
抗原表位
15

6

3

3

3

2

2

1

1

1

1

1

1
AA 261-289, C-Term
适用
39

29

15

5

5

5

5

5

4

4

4

4

4

3

2

1

1

1

1
人
宿主
51

4
兔
Compatible Secondaries
克隆类型
50

5
多克隆
标记
28

4

3

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This OTX2 antibody is un-conjugated
应用范围
39

20

13

13

13

5

5

4

3

3

2

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

预测反应

X, Zf, M

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This OTX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 261-289 amino acids from the C-terminal region of human OTX2.

克隆位点

RB17482

亚型

Ig Fraction

Top Product

Discover our top product OTX2 Primary Antibody
anti-Orthodenticle Homeobox 2 (OTX2) antibody
OTX2 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 1H12C4B5 unconjugated

anti-Orthodenticle Homeobox 2 (OTX2) (N-Term) antibody
OTX2 适用: 人, 大鼠, 小鼠, 斑马鱼, 犬, 绵羊, 兔, 马, Cow, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Orthodenticle Homeobox 2 (OTX2) antibody
OTX2 适用: 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Orthodenticle Homeobox 2 (OTX2) (AA 1-297) antibody
OTX2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Orthodenticle Homeobox 2 (OTX2) (AA 86-135) antibody
OTX2 适用: 人, 大鼠, 小鼠, 斑马鱼, 犬, 绵羊, 兔, 马, Cow, 豚鼠, Bat, Hamster, Pig, 小鸡 WB 宿主: 兔 Polyclonal unconjugated

anti-Orthodenticle Homeobox 2 (OTX2) (AA 140-280) antibody
OTX2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Orthodenticle Homeobox 2 (OTX2) antibody
OTX2 适用: 人 WB 宿主: 兔 Monoclonal unconjugated

anti-Orthodenticle Homeobox 2 (OTX2) (AA 261-289) antibody
OTX2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Orthodenticle Homeobox 2 (OTX2) (C-Term) antibody
OTX2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Orthodenticle Homeobox 2 (OTX2) (AA 102-135) antibody
OTX2 适用: 人 WB 宿主: 兔 Polyclonal RB50908 unconjugated

应用备注

WB: 1:1000. IHC-P: 1:50~100

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Masuda, Esumi: "SOX9, through interaction with microphthalmia-associated transcription factor (MITF) and OTX2, regulates BEST1 expression in the retinal pigment epithelium." in: The Journal of biological chemistry, Vol. 285, Issue 35, pp. 26933-44, (2010) (PubMed).

Chung, Licznerski, Alavian, Simeone, Lin, Martin, Vance, Isacson: "The transcription factor orthodenticle homeobox 2 influences axonal projections and vulnerability of midbrain dopaminergic neurons." in: Brain : a journal of neurology, Vol. 133, Issue Pt 7, pp. 2022-31, (2010) (PubMed).

Ashkenazi-Hoffnung, Lebenthal, Wyatt, Ragge, Dateki, Fukami, Ogata, Phillip, Gat-Yablonski: "A novel loss-of-function mutation in OTX2 in a patient with anophthalmia and isolated growth hormone deficiency." in: Human genetics, Vol. 127, Issue 6, pp. 721-9, (2010) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Gonzalez-Rodriguez, Pelcastre, Tovilla-Canales, Garcia-Ortiz, Amato-Almanza, Villanueva-Mendoza, Espinosa-Mattar, Zenteno: "Mutational screening of CHX10, GDF6, OTX2, RAX and SOX2 genes in 50 unrelated microphthalmia-anophthalmia-coloboma (MAC) spectrum cases." in: The British journal of ophthalmology, Vol. 94, Issue 8, pp. 1100-4, (2010) (PubMed).
抗原

OTX2 (Orthodenticle Homeobox 2 (OTX2))

别名

OTX2 (OTX2 产品)

别名

CPHD6 antibody, MCOPS5 antibody, E130306E05Rik antibody, id:ibd2915 antibody, zOtx2 antibody, zgc:136535 antibody, zotx-2 antibody, Xotx-2 antibody, Xotx2 antibody, otx-2 antibody, otx2 antibody, orthodenticle homeobox 2 antibody, orthodenticle homeobox 2 S homeolog antibody, orthodenticle homeobox 2 L homeolog antibody, OTX2 antibody, Otx2 antibody, otx2 antibody, otx2.S antibody, otx2.L antibody

背景

This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mice is required for proper forebrain development. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants may exist, but their full length sequences have not been determined.

分子量

31636

NCBI登录号

NP_001257452, NP_001257453, NP_001257454, NP_068374, NP_758840

UniProt

P32243

途径

Dopaminergic Neurogenesis