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NEU1 抗体 (AA 188-214)

NEU1 适用: 人 WB 宿主: 兔 Polyclonal RB42166 unconjugated
产品编号 ABIN1881576
发货至: 中国
  • 抗原 See all NEU1 抗体
    NEU1 (Sialidase 1 (Lysosomal Sialidase) (NEU1))
    抗原表位
    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 188-214
    适用
    • 49
    • 11
    • 11
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 41
    • 11
    克隆类型
    • 43
    • 9
    多克隆
    标记
    • 27
    • 8
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NEU1 antibody is un-conjugated
    应用范围
    • 40
    • 21
    • 17
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    预测反应
    B
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This NEU1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-214 amino acids from the Central region of human NEU1.
    克隆位点
    RB42166
    亚型
    Ig Fraction
    Top Product
    Discover our top product NEU1 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Caciotti, Di Rocco, Filocamo, Grossi, Traverso, dAzzo, Cavicchi, Messeri, Guerrini, Zammarchi, Donati, Morrone: "Type II sialidosis: review of the clinical spectrum and identification of a new splicing defect with chitotriosidase assessment in two patients." in: Journal of neurology, Vol. 256, Issue 11, pp. 1911-5, (2009) (PubMed).

    Lai, Chen, Wu Chou, Chang, Kao, Huang, Weng, Chen, Hwu, Lu: "A longitudinal study of Taiwanese sialidosis type 1: an insight into the concept of cherry-red spot myoclonus syndrome." in: European journal of neurology : the official journal of the European Federation of Neurological Societies, Vol. 16, Issue 8, pp. 912-9, (2009) (PubMed).

    Bonten, Campos, Zaitsev, Nourse, Waddell, Lewis, Taylor, dAzzo: "Heterodimerization of the sialidase NEU1 with the chaperone protective protein/cathepsin A prevents its premature oligomerization." in: The Journal of biological chemistry, Vol. 284, Issue 41, pp. 28430-41, (2009) (PubMed).

  • 抗原
    NEU1 (Sialidase 1 (Lysosomal Sialidase) (NEU1))
    别名
    NEU1 (NEU1 产品)
    别名
    NANH antibody, NEU antibody, SIAL1 antibody, MGC81958 antibody, AA407268 antibody, AA407316 antibody, Aglp antibody, Apl antibody, Bat-7 antibody, Bat7 antibody, G9 antibody, Map-2 antibody, Neu antibody, Neu-1 antibody, neuraminidase 1 antibody, neuraminidase 1 (lysosomal sialidase) L homeolog antibody, NEU1 antibody, neu1.L antibody, neu1 antibody, Neu1 antibody
    背景
    The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity.
    分子量
    45467
    NCBI登录号
    NP_000425
    UniProt
    Q99519
    途径
    SARS-CoV-2 Protein Interactome
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