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- 抗原 See all NEU1 抗体
- NEU1 (Sialidase 1 (Lysosomal Sialidase) (NEU1))
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抗原表位
- AA 188-214
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NEU1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 预测反应
- B
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This NEU1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-214 amino acids from the Central region of human NEU1.
- 克隆位点
- RB42166
- 亚型
- Ig Fraction
- Top Product
- Discover our top product NEU1 Primary Antibody
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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Type II sialidosis: review of the clinical spectrum and identification of a new splicing defect with chitotriosidase assessment in two patients." in: Journal of neurology, Vol. 256, Issue 11, pp. 1911-5, (2009) (PubMed).
: "A longitudinal study of Taiwanese sialidosis type 1: an insight into the concept of cherry-red spot myoclonus syndrome." in: European journal of neurology : the official journal of the European Federation of Neurological Societies, Vol. 16, Issue 8, pp. 912-9, (2009) (PubMed).
: "Heterodimerization of the sialidase NEU1 with the chaperone protective protein/cathepsin A prevents its premature oligomerization." in: The Journal of biological chemistry, Vol. 284, Issue 41, pp. 28430-41, (2009) (PubMed).
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Type II sialidosis: review of the clinical spectrum and identification of a new splicing defect with chitotriosidase assessment in two patients." in: Journal of neurology, Vol. 256, Issue 11, pp. 1911-5, (2009) (PubMed).
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- 抗原
- NEU1 (Sialidase 1 (Lysosomal Sialidase) (NEU1))
- 别名
- NEU1 (NEU1 产品)
- 别名
- NANH antibody, NEU antibody, SIAL1 antibody, MGC81958 antibody, AA407268 antibody, AA407316 antibody, Aglp antibody, Apl antibody, Bat-7 antibody, Bat7 antibody, G9 antibody, Map-2 antibody, Neu antibody, Neu-1 antibody, neuraminidase 1 antibody, neuraminidase 1 (lysosomal sialidase) L homeolog antibody, NEU1 antibody, neu1.L antibody, neu1 antibody, Neu1 antibody
- 背景
- The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity.
- 分子量
- 45467
- NCBI登录号
- NP_000425
- UniProt
- Q99519
- 途径
- SARS-CoV-2 Protein Interactome
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