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MTHFR 抗体 (AA 266-292)

MTHFR 适用: 人 WB 宿主: 兔 Polyclonal RB41196 unconjugated
产品编号 ABIN1881559
发货至: 中国
  • 抗原 See all MTHFR 抗体
    MTHFR (Methylenetetrahydrofolate Reductase (NAD(P)H) (MTHFR))
    抗原表位
    • 15
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 266-292
    适用
    • 50
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 45
    • 4
    • 2
    克隆类型
    • 49
    • 2
    多克隆
    标记
    • 21
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MTHFR antibody is un-conjugated
    应用范围
    • 38
    • 18
    • 13
    • 13
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    预测反应
    B, Pr, M
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This MTHFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 266-292 amino acids from the Central region of human MTHFR.
    克隆位点
    RB41196
    亚型
    Ig Fraction
    Top Product
    Discover our top product MTHFR Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Singh, Singh, Raman: "MTHFR A1298C polymorphism and idiopathic male infertility." in: Journal of postgraduate medicine, Vol. 56, Issue 4, pp. 267-9, (2010) (PubMed).

    Harisha, Devi, Christopher, Kruthika-Vinod: "Impact of 5,10-methylenetetrahydrofolate reductase gene polymorphism on neural tube defects." in: Journal of neurosurgery. Pediatrics, Vol. 6, Issue 4, pp. 364-7, (2010) (PubMed).

    Wu, Chang, Tsai, Lin, Wang, Tsai, Chen, Yao, Chiu, Bau, Lin: "Significant association of methylenetetrahydrofolate reductase single nucleotide polymorphisms with prostate cancer susceptibility in taiwan." in: Anticancer research, Vol. 30, Issue 9, pp. 3573-7, (2010) (PubMed).

    Magnowski, Seremak-Mrozikiewicz, Nowak-Markwitz, Kurzawińska, Drews, Spaczyński: "[No association between MTHFR 677C>T polymorphism and ovarian cancer risk in BRCA1 mutation carriers in Wielkopolska region]." in: Ginekologia polska, Vol. 81, Issue 7, pp. 506-10, (2010) (PubMed).

    Kristensen, Pedersen, Melsen, Ellehauge, Mejer: "Variants in the dihydropyrimidine dehydrogenase, methylenetetrahydrofolate reductase and thymidylate synthase genes predict early toxicity of 5-fluorouracil in colorectal cancer patients." in: The Journal of international medical research, Vol. 38, Issue 3, pp. 870-83, (2010) (PubMed).

  • 抗原
    MTHFR (Methylenetetrahydrofolate Reductase (NAD(P)H) (MTHFR))
    别名
    MTHFR (MTHFR 产品)
    别名
    DDBDRAFT_0204686 antibody, DDBDRAFT_0230137 antibody, DDB_0204686 antibody, DDB_0230137 antibody, AI323986 antibody, methylenetetrahydrofolate reductase (NAD(P)H) L homeolog antibody, methylenetetrahydrofolate reductase antibody, methylenetetrahydrofolate reductase (NAD(P)H) antibody, 5,10-methylenetetrahydrofolate reductase antibody, mthfr.L antibody, MTHFR antibody, mthfr antibody, metF antibody, DDB_G0279137 antibody, Mthfr antibody
    背景
    The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.
    分子量
    74597
    NCBI登录号
    NP_005948
    UniProt
    P42898
    途径
    Methionine Biosynthetic Process
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