This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This MCM9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 316-345 amino acids from the C-terminal region of human MCM9.
MCM9, a member of the MCM2-8 family, binds to chromatin and is required for the recruitment of the MCM2-7 helicase onto chromatin. MCM9 can form a complex with Cdt1. It is thought that MCM9 might play an important role in DNA replication since its depletion results in its inhibition.