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- 抗原 See all MAVS 抗体
- MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))
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抗原表位
- AA 1-30, N-Term
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MAVS antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This Mouse Mavs antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of mouse Mavs.
- 克隆位点
- RB42373
- 亚型
- Ig Fraction
- Top Product
- Discover our top product MAVS Primary Antibody
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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Influenza virus activates inflammasomes via its intracellular M2 ion channel." in: Nature immunology, Vol. 11, Issue 5, pp. 404-10, (2010) (PubMed).
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Influenza virus activates inflammasomes via its intracellular M2 ion channel." in: Nature immunology, Vol. 11, Issue 5, pp. 404-10, (2010) (PubMed).
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- 抗原
- MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))
- 别名
- Mavs (MAVS 产品)
- 别名
- CARDIF antibody, IPS-1 antibody, IPS1 antibody, VISA antibody, D430028G21Rik antibody, Visa antibody, cardif antibody, wu:fj20d04 antibody, zgc:158392 antibody, mitochondrial antiviral signaling protein antibody, MAVS antibody, Mavs antibody, mavs antibody
- 背景
- Required for innate immune defense against viruses. Acts downstream of DDX58 and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5). May activate the same pathways following detection of extracellular dsRNA by TLR3. May protect cells from apoptosis (By similarity).
- 分子量
- 53399
- NCBI登录号
- NP_001193314, NP_659137
- UniProt
- Q8VCF0
- 途径
- Activation of Innate immune Response, Inositol Metabolic Process, Hepatitis C
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