(3 references)-
- 抗原 See all LGMN 抗体
- LGMN (Legumain (LGMN))
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抗原表位
- AA 83-112, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LGMN antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 预测反应
- Pr
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This LGMN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 83-112 amino acids from the N-terminal region of human LGMN.
- 克隆位点
- RB41868
- 亚型
- Ig Fraction
- Top Product
- Discover our top product LGMN Primary Antibody
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anti-Legumain (LGMN) (AA 18-433) antibody
LGMN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Legumain (LGMN) (AA 18-435) antibodyLGMN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Legumain (LGMN) (AA 201-300) antibodyLGMN 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Legumain (LGMN) (AA 18-323) antibodyLGMN 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Legumain (LGMN) antibodyLGMN 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Legumain (LGMN) (AA 1-433) antibodyLGMN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Legumain (LGMN) (AA 1-433) antibodyLGMN 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Legumain (LGMN) (AA 1-433) antibodyLGMN 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Legumain (LGMN) (AA 199-312) antibodyLGMN 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Legumain (LGMN) (AA 1-433) antibodyLGMN 适用: 人 ELISA 宿主: 小鼠 Monoclonal M1 unconjugated
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- 应用备注
- WB: 1:1000. WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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: "Expression of the cysteine protease legumain in vascular lesions and functional implications in atherogenesis." in: Atherosclerosis, Vol. 201, Issue 1, pp. 53-66, (2009) (PubMed).
: "Neuroprotective actions of PIKE-L by inhibition of SET proteolytic degradation by asparagine endopeptidase." in: Molecular cell, Vol. 29, Issue 6, pp. 665-78, (2008) (PubMed).
: "Transcriptome analysis of human gastric cancer." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 16, Issue 12, pp. 942-54, (2005) (PubMed).
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: "Expression of the cysteine protease legumain in vascular lesions and functional implications in atherogenesis." in: Atherosclerosis, Vol. 201, Issue 1, pp. 53-66, (2009) (PubMed).
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- 抗原
- LGMN (Legumain (LGMN))
- 别名
- LGMN (LGMN 产品)
- 别名
- AEP antibody, LGMN1 antibody, PRSC1 antibody, AI746452 antibody, AU022324 antibody, Prsc1 antibody, MGC64351 antibody, cb173 antibody, cb460 antibody, sb:cb173 antibody, zgc:76953 antibody, wu:fa98g05 antibody, wu:fj92g08 antibody, lgmn antibody, MGC88980 antibody, DELTA VACUOLAR PROCESSING ENZYME antibody, DELTAVPE antibody, delta vacuolar processing enzyme antibody, legumain antibody, legumain L homeolog antibody, delta vacuolar processing enzyme antibody, Legumain antibody, LGMN antibody, Lgmn antibody, lgmn.L antibody, lgmn antibody, DELTA-VPE antibody, MBOO_RS07785 antibody, Odosp_3582 antibody, LOC569153 antibody
- 背景
- This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform.
- 分子量
- 49411
- NCBI登录号
- NP_001008530, NP_005597
- UniProt
- Q99538
- 途径
- Metabolism of Steroid Hormones and Vitamin D, Activation of Innate immune Response, Toll-Like Receptors Cascades
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