HLA-DQA2 抗体 (AA 39-66)
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- 抗原 See all HLA-DQA2 抗体
- HLA-DQA2 (Major Histocompatibility Complex, Class II, DQ alpha 2 (HLA-DQA2))
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抗原表位
- AA 39-66
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HLA-DQA2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This HLA-DQA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-66 amino acids from the Central region of human HLA-DQA2.
- 克隆位点
- RB42054
- 亚型
- Ig Fraction
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy." in: Nature genetics, Vol. 42, Issue 9, pp. 786-9, (2010) (PubMed).
: "Genome-wide association study in alopecia areata implicates both innate and adaptive immunity." in: Nature, Vol. 466, Issue 7302, pp. 113-7, (2010) (PubMed).
: "Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection." in: Molecular human reproduction, Vol. 16, Issue 10, pp. 770-7, (2010) (PubMed).
: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, (2010) (PubMed).
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Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy." in: Nature genetics, Vol. 42, Issue 9, pp. 786-9, (2010) (PubMed).
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- 抗原
- HLA-DQA2 (Major Histocompatibility Complex, Class II, DQ alpha 2 (HLA-DQA2))
- 别名
- HLA-DQA2 (HLA-DQA2 产品)
- 别名
- DX-ALPHA antibody, HLA-DXA antibody, major histocompatibility complex, class II, DQ alpha 2 antibody, HLA-DQA2 antibody
- 背景
- This gene belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages) and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells. [provided by RefSeq].
- 分子量
- 28033
- NCBI登录号
- NP_064440
- UniProt
- P01906
- 途径
- TCR Signaling, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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