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HIST2H3A 抗体 (C-Term)

HIST2H3A 适用: 人 WB 宿主: 兔 Polyclonal RB41556 unconjugated
产品编号 ABIN1881419
发货至: 中国
  • 抗原 See all HIST2H3A 抗体
    HIST2H3A (Histone Cluster 2, H3a (HIST2H3A))
    抗原表位
    • 15
    • 6
    • 2
    • 1
    AA 108-136, C-Term
    适用
    • 16
    • 1
    • 1
    宿主
    • 18
    克隆类型
    • 18
    多克隆
    标记
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    This HIST2H3A antibody is un-conjugated
    应用范围
    • 15
    • 15
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    预测反应
    B, M, Rat, C, Zf, X, E, D, Pig, Rb
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This HIST2H3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 108-136 amino acids from the C-terminal region of human HIST2H3A.
    克隆位点
    RB41556
    亚型
    Ig Fraction
    Top Product
    Discover our top product HIST2H3A Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Neumann, Hancock, Buning, Routh, Chapman, Somers, Owen-Hughes, van Noort, Rhodes, Chin: "A method for genetically installing site-specific acetylation in recombinant histones defines the effects of H3 K56 acetylation." in: Molecular cell, Vol. 36, Issue 1, pp. 153-63, (2009) (PubMed).

    Hurd, Bannister, Halls, Dawson, Vermeulen, Olsen, Ismail, Somers, Mann, Owen-Hughes, Gout, Kouzarides: "Phosphorylation of histone H3 Thr-45 is linked to apoptosis." in: The Journal of biological chemistry, Vol. 284, Issue 24, pp. 16575-83, (2009) (PubMed).

    Yuan, Pu, Zhang, Lou: "Histone H3-K56 acetylation is important for genomic stability in mammals." in: Cell cycle (Georgetown, Tex.), Vol. 8, Issue 11, pp. 1747-53, (2009) (PubMed).

    Chang, Zhang, Beezhold, Bhatia, Zhao, Chen, Castranova, Shi, Chen: "Sustained JNK1 activation is associated with altered histone H3 methylations in human liver cancer." in: Journal of hepatology, Vol. 50, Issue 2, pp. 323-33, (2009) (PubMed).

    Kobza, Sarath, Zempleni: "Prokaryotic BirA ligase biotinylates K4, K9, K18 and K23 in histone H3." in: BMB reports, Vol. 41, Issue 4, pp. 310-5, (2008) (PubMed).

  • 抗原
    HIST2H3A (Histone Cluster 2, H3a (HIST2H3A))
    别名
    HIST2H3A (HIST2H3A 产品)
    别名
    H3/n antibody, H3/o antibody, histone cluster 2 H3 family member a antibody, HIST2H3A antibody
    背景
    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated, this record represents the telomeric copy. [provided by RefSeq].
    分子量
    15388
    NCBI登录号
    NP_001005464, NP_001116847, NP_066403
    UniProt
    Q71DI3
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