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- 抗原 See all HIST2H3A 抗体
- HIST2H3A (Histone Cluster 2, H3a (HIST2H3A))
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抗原表位
- AA 108-136, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HIST2H3A antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 预测反应
- B, M, Rat, C, Zf, X, E, D, Pig, Rb
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This HIST2H3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 108-136 amino acids from the C-terminal region of human HIST2H3A.
- 克隆位点
- RB41556
- 亚型
- Ig Fraction
- Top Product
- Discover our top product HIST2H3A Primary Antibody
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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A method for genetically installing site-specific acetylation in recombinant histones defines the effects of H3 K56 acetylation." in: Molecular cell, Vol. 36, Issue 1, pp. 153-63, (2009) (PubMed).
: "Phosphorylation of histone H3 Thr-45 is linked to apoptosis." in: The Journal of biological chemistry, Vol. 284, Issue 24, pp. 16575-83, (2009) (PubMed).
: "Histone H3-K56 acetylation is important for genomic stability in mammals." in: Cell cycle (Georgetown, Tex.), Vol. 8, Issue 11, pp. 1747-53, (2009) (PubMed).
: "Sustained JNK1 activation is associated with altered histone H3 methylations in human liver cancer." in: Journal of hepatology, Vol. 50, Issue 2, pp. 323-33, (2009) (PubMed).
: "Prokaryotic BirA ligase biotinylates K4, K9, K18 and K23 in histone H3." in: BMB reports, Vol. 41, Issue 4, pp. 310-5, (2008) (PubMed).
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A method for genetically installing site-specific acetylation in recombinant histones defines the effects of H3 K56 acetylation." in: Molecular cell, Vol. 36, Issue 1, pp. 153-63, (2009) (PubMed).
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- 抗原
- HIST2H3A (Histone Cluster 2, H3a (HIST2H3A))
- 别名
- HIST2H3A (HIST2H3A 产品)
- 别名
- H3/n antibody, H3/o antibody, histone cluster 2 H3 family member a antibody, HIST2H3A antibody
- 背景
- Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated, this record represents the telomeric copy. [provided by RefSeq].
- 分子量
- 15388
- NCBI登录号
- NP_001005464, NP_001116847, NP_066403
- UniProt
- Q71DI3
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