This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This HERC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-77 amino acids from the N-terminal region of human HERC3.
5730409F18Rik antibody, AI646603 antibody, mKIAA0032 antibody, HECT and RLD domain containing E3 ubiquitin protein ligase 3 antibody, HECT and RLD domain containing E3 ubiquitin protein ligase 3 L homeolog antibody, probable E3 ubiquitin-protein ligase HERC3 antibody, hect domain and RLD 3 antibody, HERC3 antibody, herc3.L antibody, herc3 antibody, LOC100539754 antibody, LOC100563151 antibody, Herc3 antibody
背景
HERC3 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).