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- 抗原 See all GUCA1C 抗体
- GUCA1C (Guanylate Cyclase Activator 1C (GUCA1C))
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抗原表位
- AA 171-199, C-Term
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GUCA1C antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This GUCA1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-199 amino acids from the C-terminal region of human GUCA1C.
- 克隆位点
- RB42656
- 亚型
- Ig Fraction
- Top Product
- Discover our top product GUCA1C Primary Antibody
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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The crystal structure of GCAP3 suggests molecular mechanism of GCAP-linked cone dystrophies." in: Journal of molecular biology, Vol. 359, Issue 2, pp. 266-75, (2006) (PubMed).
: "Characterization of retinal guanylate cyclase-activating protein 3 (GCAP3) from zebrafish to man." in: The European journal of neuroscience, Vol. 15, Issue 1, pp. 63-78, (2002) (PubMed).
: "Molecular characterization of a third member of the guanylyl cyclase-activating protein subfamily." in: The Journal of biological chemistry, Vol. 274, Issue 10, pp. 6526-35, (1999) (PubMed).
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The crystal structure of GCAP3 suggests molecular mechanism of GCAP-linked cone dystrophies." in: Journal of molecular biology, Vol. 359, Issue 2, pp. 266-75, (2006) (PubMed).
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- 抗原
- GUCA1C (Guanylate Cyclase Activator 1C (GUCA1C))
- 别名
- GUCA1C (GUCA1C 产品)
- 别名
- gcap3 antibody, GCAP3 antibody, guanylate cyclase activator 1C antibody, guca1c antibody, GUCA1C antibody
- 背景
- GUCA1C stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low and inhibits guanylyl cyclases when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of guanylyl cyclase (GC) is a key event in recovery of the dark state of rod photoreceptors following light exposure.
- 分子量
- 23822
- NCBI登录号
- NP_005450
- UniProt
- O95843
- 途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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