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GAB2 抗体 (N-Term)

GAB2 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB21209 unconjugated
产品编号 ABIN1881358
发货至: 中国
  • 抗原 See all GAB2 抗体
    GAB2 (GRB2-Associated Binding Protein 2 (GAB2))
    抗原表位
    • 24
    • 21
    • 16
    • 11
    • 10
    • 7
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 3-30, N-Term
    适用
    • 123
    • 91
    • 85
    • 3
    • 3
    • 3
    • 3
    宿主
    • 121
    • 2
    • 1
    克隆类型
    • 123
    • 1
    多克隆
    标记
    • 40
    • 8
    • 5
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    • 5
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    • 5
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    • 4
    • 3
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    • 3
    • 3
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    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    This GAB2 antibody is un-conjugated
    应用范围
    • 85
    • 41
    • 39
    • 39
    • 19
    • 16
    • 13
    • 9
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    预测反应
    M, Rat
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This GAB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 3-30 amino acids from the N-terminal region of human GAB2.
    克隆位点
    RB21209
    亚型
    Ig Fraction
    Top Product
    Discover our top product GAB2 Primary Antibody
  • 应用备注
    WB: 1:1000. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Dunn, Cheung, Agarwalla, Thomas, Zektser, Karst, Boehm, Weir, Berlin, Zou, Getz, Liu, Hirsch, Vazquez, Root, Beroukhim, Drapkin, Hahn: "In vivo multiplexed interrogation of amplified genes identifies GAB2 as an ovarian cancer oncogene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 3, pp. 1102-7, (2014) (PubMed).

    Yamasaki, Nishida, Hibi, Sakuma, Shiina, Takeuchi, Ohnishi, Hirano, Saito: "Docking protein Gab2 is phosphorylated by ZAP-70 and negatively regulates T cell receptor signaling by recruitment of inhibitory molecules." in: The Journal of biological chemistry, Vol. 276, Issue 48, pp. 45175-83, (2001) (PubMed).

  • 抗原
    GAB2 (GRB2-Associated Binding Protein 2 (GAB2))
    别名
    GAB2 (GAB2 产品)
    别名
    GAB2 antibody, AI463667 antibody, D130058I17Rik antibody, p97 antibody, GRB2 associated binding protein 2 antibody, GRB2-associated binding protein 2 antibody, growth factor receptor bound protein 2-associated protein 2 antibody, GAB2 antibody, gab2 antibody, Gab2 antibody
    背景
    GAB2 is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor.
    分子量
    74458
    NCBI登录号
    NP_036428, NP_536739
    UniProt
    Q9UQC2
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, BCR Signaling, Warburg Effect
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