(2 references)-
- 抗原 See all EXOSC2 抗体
- EXOSC2 (Exosome Component 2 (EXOSC2))
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抗原表位
- AA 1-30, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EXOSC2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This EXOSC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human EXOSC2.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product EXOSC2 Primary Antibody
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anti-Exosome Component 2 (EXOSC2) (AA 1-293) antibody
EXOSC2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Exosome Component 2 (EXOSC2) (AA 1-293) antibodyEXOSC2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Exosome Component 2 (EXOSC2) (AA 71-160) antibodyEXOSC2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Exosome Component 2 (EXOSC2) (N-Term) antibodyEXOSC2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, Pig, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Exosome Component 2 (EXOSC2) (AA 71-160) antibodyEXOSC2 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4B6 unconjugated
anti-Exosome Component 2 (EXOSC2) (N-Term) antibodyEXOSC2 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Exosome Component 2 (EXOSC2) (AA 143-192) antibodyEXOSC2 适用: 人, 小鼠, 犬, Cow, 豚鼠, 马, Pig, 兔, 猴, Bat, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Exosome Component 2 (EXOSC2) (Middle Region) antibodyEXOSC2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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- 抗原
- EXOSC2 (Exosome Component 2 (EXOSC2))
- 别名
- EXOSC2 (EXOSC2 产品)
- 别名
- EXOSC2 antibody, exosc2 antibody, MGC97533 antibody, RRP4 antibody, Rrp4p antibody, hRrp4p antibody, p7 antibody, Rrp4 antibody, fa97b01 antibody, wu:fa97b01 antibody, zgc:110117 antibody, exosome component 2 antibody, exosome component 2 L homeolog antibody, EXOSC2 antibody, exosc2 antibody, Bm1_33895 antibody, PTRG_00114 antibody, Exosc2 antibody, exosc2.L antibody
- 背景
- Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC2 as peripheral part of the Exo-9 complex stabilizes the hexameric ring of RNase PH-domain subunits through contacts with EXOSC4 and EXOSC7.
- 分子量
- 32789
- NCBI登录号
- NP_055100
- UniProt
- Q13868
- 途径
- SARS-CoV-2 Protein Interactome
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