我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

p300 抗体 (pSer1834)

Name: p300 抗体 (pSer1834)
SKU: ABIN1881299
Availability: OutOfStock

EP300 适用: 人 DB 宿主: 兔 Polyclonal RB41431 unconjugated

Dot blot analysis of E Antibody (Phospho ) Phospho-specific Pab (ABIN1881299 and ABIN2839953) on nitrocellulose membrane. (p300 抗体 (pSer1834))

1 image

(5 references)

产品编号 ABIN1881299

发货至: 中国

Datasheet as PDF

抗原 See all p300 (EP300) 抗体

p300 (EP300) (E1A Binding Protein P300 (EP300))
抗原表位
35

11

5

4

3

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer1834
适用
87

43

27

15

1

1

1

1

1

1
人
宿主
79

12
兔
Compatible Secondaries
克隆类型
80

11
多克隆
标记
52

6

5

5

3

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This p300 antibody is un-conjugated
应用范围
65

43

36

19

17

15

15

13

11

7

5

3

2

2

2

1

1

1
Dot Blot (DB)

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This EP300 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1834 of human EP300.

克隆位点

RB41431

亚型

Ig Fraction

Top Product

Discover our top product EP300 Primary Antibody
anti-E1A Binding Protein P300 (EP300) (AA 1-270) antibody
EP300 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-E1A Binding Protein P300 (EP300) (AA 731-830) antibody
EP300 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 1B1 unconjugated

anti-E1A Binding Protein P300 (EP300) (AA 2065-2414) antibody
EP300 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-E1A Binding Protein P300 (EP300) (AA 1351-1601) antibody
EP300 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-E1A Binding Protein P300 (EP300) (AA 1-158) antibody
EP300 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-E1A Binding Protein P300 (EP300) antibody
EP300 适用: 人 WB, IP, IF, ICC, ChIP, ChIP-seq 宿主: 小鼠 Monoclonal NM11 unconjugated

anti-E1A Binding Protein P300 (EP300) (AA 2124-2397) antibody
EP300 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-E1A Binding Protein P300 (EP300) (N-Term) antibody
EP300 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-E1A Binding Protein P300 (EP300) (AA 731-831) antibody
EP300 适用: 人 WB, IHC, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 1B1 unconjugated

anti-E1A Binding Protein P300 (EP300) antibody
EP300 适用: 人 ELISA 宿主: 小鼠 Monoclonal 7D8A6 unconjugated

应用备注

DB: 1:500

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Zhang, Zhang, Rui, Liu: "p300-mediated acetylation stabilizes the Th-inducing POK factor." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 7, pp. 3960-9, (2010) (PubMed).

Vempati, Jayani, Notani, Sengupta, Galande, Haldar: "p300-mediated acetylation of histone H3 lysine 56 functions in DNA damage response in mammals." in: The Journal of biological chemistry, Vol. 285, Issue 37, pp. 28553-64, (2010) (PubMed).

Reynoird, Schwartz, Delvecchio, Sadoul, Meyers, Mukherjee, Caron, Kimura, Rousseaux, Cole, Panne, French, Khochbin: "Oncogenesis by sequestration of CBP/p300 in transcriptionally inactive hyperacetylated chromatin domains." in: The EMBO journal, Vol. 29, Issue 17, pp. 2943-52, (2010) (PubMed).

Jang, Choi, Jeong, Lee: "Phosphorylation of p300 by ATM controls the stability of NBS1." in: Biochemical and biophysical research communications, Vol. 397, Issue 4, pp. 637-43, (2010) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).
抗原

p300 (EP300) (E1A Binding Protein P300 (EP300))

别名

EP300 (EP300 产品)

别名

KAT3B antibody, RSTS2 antibody, p300 antibody, A430090G16 antibody, A730011L11 antibody, p300 HAT antibody, E1A binding protein p300 antibody, histone acetyltransferase p300 antibody, EP300 antibody, LOC446056 antibody, ep300 antibody, Ep300 antibody

背景

This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.

分子量

264161

NCBI登录号

NP_001420

UniProt

Q09472

途径

p53 Pathway, Notch Signaling, Interferon-gamma Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Regulation of Cell Size