EIF3E 抗体 (AA 248-276)
(5 references)-
- 抗原 See all EIF3E 抗体
- EIF3E (Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E))
-
抗原表位
- AA 248-276
-
适用
- 人, 斑马鱼
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This EIF3E antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 预测反应
- X, B, C, Pr, M, Rat
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This EIF3E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-276 amino acids from the Central region of human EIF3E.
- 克隆位点
- RB40515
- 亚型
- Ig Fraction
- Top Product
- Discover our top product EIF3E Primary Antibody
-
anti-Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) (Middle Region) antibody
EIF3E 适用: 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 马, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) (AA 346-445) antibodyEIF3E 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) (AA 1-445) antibodyEIF3E 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) (AA 36-85) antibodyEIF3E 适用: 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 马, 兔, 豚鼠, 猴, Pig, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) (C-Term) antibodyEIF3E 适用: 人, 小鼠, 大鼠, Cow, 犬, 猴 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) (N-Term) antibodyEIF3E 适用: 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 马, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) antibodyEIF3E 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) (C-Term) antibodyVerified EIF3E 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) (AA 360-409) antibodyEIF3E 适用: 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 马, 兔, 豚鼠, 猴, Pig, Bat, 非洲爪蟾, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) (AA 1-445) antibodyEIF3E 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- WB: 1:1000. WB: 1:1000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
-
-
: "An oncogenic role of eIF3e/INT6 in human breast cancer." in: Oncogene, Vol. 29, Issue 28, pp. 4080-9, (2010) (PubMed).
: "Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 47, pp. 18139-44, (2008) (PubMed).
: "Human INT6/eIF3e is required for nonsense-mediated mRNA decay." in: EMBO reports, Vol. 8, Issue 6, pp. 596-602, (2007) (PubMed).
: "Reconstitution reveals the functional core of mammalian eIF3." in: The EMBO journal, Vol. 26, Issue 14, pp. 3373-83, (2007) (PubMed).
: "Mid-region parathyroid hormone-related protein (PTHrP) and gene expression of MDA-MB231 breast cancer cells." in: Biological chemistry, Vol. 388, Issue 5, pp. 457-65, (2007) (PubMed).
-
: "An oncogenic role of eIF3e/INT6 in human breast cancer." in: Oncogene, Vol. 29, Issue 28, pp. 4080-9, (2010) (PubMed).
-
- 抗原
- EIF3E (Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E))
- 别名
- EIF3E (EIF3E 产品)
- 别名
- EIF3-P48 antibody, EIF3S6 antibody, INT6 antibody, eIF3-p46 antibody, 48kDa antibody, Eif3s6 antibody, Int6 antibody, eIF3-p48 antibody, eif3-p48 antibody, eif3s6 antibody, eif3s6-A antibody, eIF3e antibody, eIF3-S6 antibody, eif3s6-B antibody, EIF3SE antibody, eif3s6b antibody, im:7147439 antibody, QtsA-18056 antibody, eukaryotic translation initiation factor 3 subunit E antibody, eukaryotic translation initiation factor 3, subunit E antibody, eukaryotic translation initiation factor 3 subunit E L homeolog antibody, eukaryotic translation initiation factor 3 subunit 6 antibody, eukaryotic translation initiation factor 3 subunit E S homeolog antibody, eukaryotic translation initiation factor 3, subunit E, a antibody, Eukaryotic translation initiation factor 3 subunit E antibody, eukaryotic translation initiation factor 3, subunit E, b antibody, EIF3E antibody, Eif3e antibody, eif3e antibody, eif3e.L antibody, LOC692936 antibody, eif3e.S antibody, eif3ea antibody, eif-3.E antibody, eif3eb antibody, LOC108348260 antibody, int6 antibody
- 背景
- Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Required for nonsense-mediated mRNA decay (NMD), may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.
- 分子量
- 52221
- NCBI登录号
- NP_001559
- UniProt
- P60228
- 途径
- Ribonucleoprotein Complex Subunit Organization, Hepatitis C
-
