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DYRK1A 抗体 (C-Term)

DYRK1A 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB40563 unconjugated
产品编号 ABIN1881275
发货至: 中国
  • 抗原 See all DYRK1A 抗体
    DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))
    抗原表位
    • 15
    • 10
    • 8
    • 7
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 718-745, C-Term
    适用
    • 68
    • 29
    • 22
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 小鼠
    宿主
    • 62
    • 4
    • 2
    • 1
    克隆类型
    • 65
    • 4
    多克隆
    标记
    • 38
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DYRK1A antibody is un-conjugated
    应用范围
    • 69
    • 38
    • 14
    • 13
    • 13
    • 11
    • 8
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This Mouse Dyrk1a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 718-745 amino acids from the C-terminal region of mouse Dyrk1a.
    克隆位点
    RB40563
    亚型
    Ig Fraction
    Top Product
    Discover our top product DYRK1A Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Park, Oh, Yoo, Jung, Song, Lee, Seo, Chung: "Dyrk1A phosphorylates p53 and inhibits proliferation of embryonic neuronal cells." in: The Journal of biological chemistry, Vol. 285, Issue 41, pp. 31895-906, (2010) (PubMed).

    Kurabayashi, Hirota, Sakai, Sanada, Fukada: "DYRK1A and glycogen synthase kinase 3beta, a dual-kinase mechanism directing proteasomal degradation of CRY2 for circadian timekeeping." in: Molecular and cellular biology, Vol. 30, Issue 7, pp. 1757-68, (2010) (PubMed).

    Guo, Williams, Schug, Li: "DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1." in: The Journal of biological chemistry, Vol. 285, Issue 17, pp. 13223-32, (2010) (PubMed).

    Lee, Ha, Kim, Kim, Chang, Song, Kim: "Negative feedback Inhibition of NFATc1 by DYRK1A regulates bone homeostasis." in: The Journal of biological chemistry, Vol. 284, Issue 48, pp. 33343-51, (2009) (PubMed).

  • 抗原
    DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))
    别名
    Dyrk1a (DYRK1A 产品)
    背景
    Dyrk1a may play a role in a signaling pathway regulating nuclear functions of cell proliferation. Phosphorylates serine, threonine and tyrosine residues in its sequence and in exogenous substrates.
    分子量
    85494
    NCBI登录号
    NP_001106860, NP_031916
    UniProt
    Q61214
    途径
    Mitotic G1-G1/S Phases
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