Cullin 4B 抗体 (AA 250-278)
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- 抗原 See all Cullin 4B (CUL4B) 抗体
- Cullin 4B (CUL4B)
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抗原表位
- AA 250-278
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Cullin 4B antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 预测反应
- M
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This CUL4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-278 amino acids from the Central region of human CUL4B.
- 克隆位点
- RB42521
- 亚型
- Ig Fraction
- Top Product
- Discover our top product CUL4B Primary Antibody
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- 应用备注
- WB: 1:1000. WB: 1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase." in: Cancer cell, Vol. 18, Issue 4, pp. 329-40, (2010) (PubMed).
: "Mutations in Cullin 4B result in a human syndrome associated with increased camptothecin-induced topoisomerase I-dependent DNA breaks." in: Human molecular genetics, Vol. 19, Issue 7, pp. 1324-34, (2010) (PubMed).
: "Cullins in human intra-uterine growth restriction: expressional and epigenetic alterations." in: Placenta, Vol. 31, Issue 2, pp. 151-7, (2010) (PubMed).
: "A novel nonsense mutation in CUL4B gene in three brothers with X-linked mental retardation syndrome." in: Clinical genetics, Vol. 77, Issue 2, pp. 141-4, (2010) (PubMed).
: "CRL4(Cdt2) regulates cell proliferation and histone gene expression by targeting PR-Set7/Set8 for degradation." in: Molecular cell, Vol. 40, Issue 1, pp. 9-21, (2010) (PubMed).
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Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase." in: Cancer cell, Vol. 18, Issue 4, pp. 329-40, (2010) (PubMed).
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- 抗原
- Cullin 4B (CUL4B)
- 别名
- CUL4B (CUL4B 产品)
- 别名
- MRXHF2 antibody, MRXS15 antibody, MRXSC antibody, SFM2 antibody, 2700050M05Rik antibody, AA409770 antibody, CUL-4B antibody, mKIAA0695 antibody, RGD1564494 antibody, im:7140950 antibody, im:7150765 antibody, MGC115611 antibody, Tb03.1J15.620 antibody, sfm2 antibody, mrxsc antibody, mrxhf2 antibody, cullin 4B antibody, cullin 4B S homeolog antibody, CUL4B antibody, Cul4b antibody, cul4b antibody, cul4b.S antibody, Tb927.3.1290 antibody
- 背景
- This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
- 分子量
- 103982
- NCBI登录号
- NP_001073341, NP_003579
- UniProt
- Q13620
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