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- 抗原 See all CSF2RA 抗体
- CSF2RA (Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA))
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抗原表位
- AA 366-394, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CSF2RA antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This CSF2RA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 366-394 amino acids from the C-terminal region of human CSF2RA.
- 克隆位点
- RB40748
- 亚型
- Ig Fraction
- Top Product
- Discover our top product CSF2RA Primary Antibody
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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The Ig-like domain of human GM-CSF receptor alpha plays a critical role in cytokine binding and receptor activation." in: The Biochemical journal, Vol. 426, Issue 3, pp. 307-17, (2010) (PubMed).
: "Pulmonary alveolar proteinosis caused by deletion of the GM-CSFRalpha gene in the X chromosome pseudoautosomal region 1." in: The Journal of experimental medicine, Vol. 205, Issue 12, pp. 2711-6, (2008) (PubMed).
: "The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation." in: Cell, Vol. 134, Issue 3, pp. 496-507, (2008) (PubMed).
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The Ig-like domain of human GM-CSF receptor alpha plays a critical role in cytokine binding and receptor activation." in: The Biochemical journal, Vol. 426, Issue 3, pp. 307-17, (2010) (PubMed).
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- 抗原
- CSF2RA (Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA))
- 别名
- CSF2RA (CSF2RA 产品)
- 别名
- CD116 antibody, CDw116 antibody, CSF2R antibody, CSF2RAX antibody, CSF2RAY antibody, CSF2RX antibody, CSF2RY antibody, GM-CSF-R-alpha antibody, GMCSFR antibody, GMR antibody, SMDP4 antibody, Csfgmra antibody, GM-CSF-Ra antibody, GM-CSFR antibody, colony stimulating factor 2 receptor, alpha antibody, colony stimulating factor 2 receptor alpha subunit antibody, colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) antibody, CSF2RA antibody, Csf2ra antibody
- 背景
- The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble.
- 分子量
- 46207
- NCBI登录号
- NP_001155001, NP_001155002, NP_001155003, NP_001155004, NP_006131, NP_758448, NP_758449, NP_758450, NP_758452
- UniProt
- P15509
- 途径
- JAK/STAT Signaling
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