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- 抗原 See all CREB3 抗体
- CREB3 (CAMP Responsive Element Binding Protein 3 (CREB3))
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抗原表位
- AA 66-94, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CREB3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This CREB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the N-terminal region of human CREB3.
- 克隆位点
- RB42213
- 亚型
- Ig Fraction
- Top Product
- Discover our top product CREB3 Primary Antibody
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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HDAC3 selectively represses CREB3-mediated transcription and migration of metastatic breast cancer cells." in: Cellular and molecular life sciences : CMLS, Vol. 67, Issue 20, pp. 3499-510, (2010) (PubMed).
: "A novel protein, Luman/CREB3 recruitment factor, inhibits Luman activation of the unfolded protein response." in: Molecular and cellular biology, Vol. 28, Issue 12, pp. 3952-66, (2008) (PubMed).
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HDAC3 selectively represses CREB3-mediated transcription and migration of metastatic breast cancer cells." in: Cellular and molecular life sciences : CMLS, Vol. 67, Issue 20, pp. 3499-510, (2010) (PubMed).
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- 抗原
- CREB3 (CAMP Responsive Element Binding Protein 3 (CREB3))
- 别名
- CREB3 (CREB3 产品)
- 别名
- LUMAN antibody, LZIP antibody, AU044960 antibody, AW538053 antibody, C80076 antibody, LZIP-1 antibody, LZIP-2 antibody, Luman antibody, creb3 antibody, luman antibody, lzip antibody, cAMP responsive element binding protein 3 antibody, cAMP responsive element binding protein 3 S homeolog antibody, CREB3 antibody, Creb3 antibody, creb3.S antibody
- 背景
- This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-response element and regulates cell proliferation. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. This protein also plays a role in leukocyte migration, tumor suppression, and endoplasmic reticulum stress-associated protein degradation. Additional transcript variants have been identified, but their biological validity has not been determined.
- 分子量
- 41379
- NCBI登录号
- NP_006359
- UniProt
- O43889
- 途径
- Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Maintenance of Protein Location, Unfolded Protein Response
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