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CLDN14 抗体 (C-Term)

CLDN14 适用: 人 WB 宿主: 兔 Polyclonal RB42184 unconjugated
产品编号 ABIN1881208
发货至: 中国
  • 抗原 See all CLDN14 抗体
    CLDN14 (Claudin 14 (CLDN14))
    抗原表位
    • 12
    • 8
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 172-200, C-Term
    适用
    • 34
    • 11
    • 2
    • 1
    宿主
    • 30
    • 3
    • 1
    克隆类型
    • 32
    • 2
    多克隆
    标记
    • 17
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CLDN14 antibody is un-conjugated
    应用范围
    • 25
    • 19
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This CLDN14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-200 amino acids from the C-terminal region of human CLDN14.
    克隆位点
    RB42184
    亚型
    Ig Fraction
    Top Product
    Discover our top product CLDN14 Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Thorleifsson, Holm, Edvardsson, Walters, Styrkarsdottir, Gudbjartsson, Sulem, Halldorsson, de Vegt, dAncona, den Heijer, Franzson, Christiansen, Alexandersen, Rafnar, Kristjansson: "Sequence variants in the CLDN14 gene associate with kidney stones and bone mineral density." in: Nature genetics, Vol. 41, Issue 8, pp. 926-30, (2009) (PubMed).

    Belguith, Tlili, Dhouib, Ben Rebeh, Lahmar, Charfeddine, Driss, Ghorbel, Ayadi, Masmoudi: "Mutation in gap and tight junctions in patients with non-syndromic hearing loss." in: Biochemical and biophysical research communications, Vol. 385, Issue 1, pp. 1-5, (2009) (PubMed).

    Hanna, Kruskal, Ezekowitz, Bloom, Collier: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, (1996) (PubMed).

  • 抗原
    CLDN14 (Claudin 14 (CLDN14))
    别名
    CLDN14 (CLDN14 产品)
    别名
    claudin-14 antibody, CLDN14 antibody, DFNB29 antibody, AI851731 antibody, claudin 14 L homeolog antibody, claudin 14 antibody, cldn14.L antibody, CLDN14 antibody, Cldn14 antibody
    背景
    Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. The encoded protein also binds specifically to the WW domain of Yes-associated protein. Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. It is also reported that four synonymous variants in this gene are associated with kidney stones and reduced bone mineral density. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].
    分子量
    25699
    NCBI登录号
    NP_001139549, NP_001139550, NP_001139551, NP_036262, NP_652763
    UniProt
    O95500
    途径
    Cell-Cell Junction Organization, Hepatitis C
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