This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This CLCN5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-41 amino acids from the N-terminal region of human CLCN5.
CLCN5
适用: 人
IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 350
应用备注
WB: 1:1000
限制
仅限研究用
状态
Liquid
缓冲液
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
有效期
6 months
Smith, Lippiat: "Voltage-dependent charge movement associated with activation of the CLC-5 2Cl-/1H+ exchanger." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 24, Issue 10, pp. 3696-705, (2010) (PubMed).
Wellhauser, DAntonio, Bear: "ClC transporters: discoveries and challenges in defining the mechanisms underlying function and regulation of ClC-5." in: Pflügers Archiv : European journal of physiology, Vol. 460, Issue 2, pp. 543-57, (2010) (PubMed).
Picollo, Malvezzi, Accardi: "Proton block of the CLC-5 Cl-/H+ exchanger." in: The Journal of general physiology, Vol. 135, Issue 6, pp. 653-9, (2010) (PubMed).
White: "On the position and value of those Lesions of the Brain which cause a rise of Temperature." in: The Journal of physiology, Vol. 12, Issue 3, pp. 233-298.3, (2007) (PubMed).
This gene encodes a member of the ClC family of chloride ion channels and ion transporters. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].