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- 抗原 See all CDKN3 抗体
- CDKN3 (Cyclin-Dependent Kinase Inhibitor 3 (CDKN3))
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抗原表位
- AA 39-68, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CDKN3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This CDKN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-68 amino acids from the N-terminal region of human CDKN3.
- 克隆位点
- RB42328
- 亚型
- Ig Fraction
- Top Product
- Discover our top product CDKN3 Primary Antibody
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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High expression levels of IKKalpha and IKKbeta are necessary for the malignant properties of liver cancer." in: International journal of cancer. Journal international du cancer, Vol. 126, Issue 5, pp. 1263-74, (2010) (PubMed).
: "An approach based on a genome-wide association study reveals candidate loci for narcolepsy." in: Human genetics, Vol. 128, Issue 4, pp. 433-41, (2010) (PubMed).
: "KAP1 dictates p53 response induced by chemotherapeutic agents via Mdm2 interaction." in: Biochemical and biophysical research communications, Vol. 351, Issue 1, pp. 216-22, (2006) (PubMed).
: "Transcriptional repression activity of PAX3 is modulated by competition between corepressor KAP1 and heterochromatin protein 1." in: Biochemical and biophysical research communications, Vol. 349, Issue 2, pp. 573-81, (2006) (PubMed).
: "Binding of HTm4 to cyclin-dependent kinase (Cdk)-associated phosphatase (KAP).Cdk2.cyclin A complex enhances the phosphatase activity of KAP, dissociates cyclin A, and facilitates KAP..." in: The Journal of biological chemistry, Vol. 280, Issue 17, pp. 17235-42, (2005) (PubMed).
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High expression levels of IKKalpha and IKKbeta are necessary for the malignant properties of liver cancer." in: International journal of cancer. Journal international du cancer, Vol. 126, Issue 5, pp. 1263-74, (2010) (PubMed).
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- 抗原
- CDKN3 (Cyclin-Dependent Kinase Inhibitor 3 (CDKN3))
- 别名
- CDKN3 (CDKN3 产品)
- 别名
- CDI1 antibody, CIP2 antibody, KAP antibody, KAP1 antibody, CDKN3 antibody, 2410006H10Rik antibody, K24G6.15 antibody, K24G6_15 antibody, KIP-RELATED PROTEIN 3 antibody, KRP3 antibody, inhibitor/interactor with cyclin-dependent kinase antibody, cyclin dependent kinase inhibitor 3 antibody, cyclin-dependent kinase inhibitor 3 antibody, inhibitor/interactor with cyclin-dependent kinase antibody, CDKN3 antibody, cdkn3 antibody, Cdkn3 antibody, ICK6 antibody
- 背景
- The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- 分子量
- 23805
- NCBI登录号
- NP_001124323, NP_005183
- UniProt
- Q16667
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