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- 抗原 See all CDK14 抗体
- CDK14 (Cyclin-Dependent Kinase 14 (CDK14))
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抗原表位
- AA 45-72, N-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CDK14 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This Mouse Cdk14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-72 amino acids from the N-terminal region of mouse Cdk14.
- 克隆位点
- RB40562
- 亚型
- Ig Fraction
- Top Product
- Discover our top product CDK14 Primary Antibody
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 45, pp. 14309-22, (2009) (PubMed).
: "Cyclin Y, a novel membrane-associated cyclin, interacts with PFTK1." in: FEBS letters, Vol. 583, Issue 13, pp. 2171-8, (2009) (PubMed).
: "
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Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 45, pp. 14309-22, (2009) (PubMed).
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- 抗原
- CDK14 (Cyclin-Dependent Kinase 14 (CDK14))
- 别名
- Cdk14 (CDK14 产品)
- 别名
- PFTK1 antibody, PFTAIRE1 antibody, Pftk1 antibody, mKIAA0834 antibody, pftaire1 antibody, pftk1 antibody, cyclin dependent kinase 14 antibody, cyclin-dependent kinase 14 antibody, cyclin-dependent kinase 14 L homeolog antibody, CDK14 antibody, Cdk14 antibody, cdk14.L antibody
- 背景
- Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport (By similarity).
- 分子量
- 52996
- NCBI登录号
- NP_035204
- UniProt
- O35495
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